Evidence map›Paper›PMID 34266492›Full record

ArticleMaternal health, neonatology and perinatology2021

Incidence and determinants of perinatal mortality among women with obstructed labour in eastern Uganda: a prospective cohort study.

Milton W Musaba, Grace Ndeezi, Justus K Barageine, Andrew D Weeks, Julius N Wandabwa, David Mukunya, Paul Waako, Beatrice Odongkara, Agnes Arach, Kenneth Tulya-Muhika Mugabe and 3 more

Open access · goldAbstract read
In one paragraph

Article in Maternal health, neonatology and perinatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
5.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 3 countries.

Milton W MusabaDepartment of Obstetrics and Gynaecology, Mbale Regional Referral and Teaching Hospital, Mbale, Uganda. miltonmusaba@gmail.com.ORCID http://orcid.org/0000-0003-4145-4044
Grace NdeeziDepartment of Paediatrics and Child Health, School of Medicine, Makerere University College of Health Sciences, Kampala, Uganda.
Justus K BarageineDepartment of Obstetrics & Gynaecology, School of Medicine, Makerere University College of Health Sciences, Kampala, Uganda.
Andrew D WeeksSanyu Research Unit, University of Liverpool/Liverpool Women's Hospital, Liverpool, UK.
Julius N WandabwaDepartment of Obstetrics and Gynaecology, Busitema University Faculty of Health Sciences, Mbale, Uganda.
David MukunyaDepartment of Public and Community Health, Busitema University Faculty of Health Sciences, Mbale, Uganda.
Paul WaakoDepartment of Pharmacology and Therapeutics, Busitema University Faculty of Health Sciences, Mbale, Uganda.
Beatrice OdongkaraDepartment of Paediatrics and Child Health, Gulu University, Gulu, Uganda.
Agnes ArachDepartment of Nursing and Midwifery, Lira University, Lira, Uganda.
Kenneth Tulya-Muhika MugabeDepartment of Obstetrics and Gynaecology, Mbale Regional Referral and Teaching Hospital, Mbale, Uganda.
Agnes Kasede NapyoDepartment of Public and Community Health, Busitema University Faculty of Health Sciences, Mbale, Uganda.
Victoria NankabirwaDepartment of Epidemiology and Biostatistics, School of Public Health, Makerere University College of Health Sciences, Kampala, Uganda.
James K TumwineDepartment of Paediatrics and Child Health, School of Medicine, Makerere University College of Health Sciences, Kampala, Uganda.
Busitema University · UGMakerere University · UGMbale Hospital · UGGulu University · UGLira Hospital · UGUniversity of Bergen · NOUniversity of Liverpool · GB

Funding

Survival Pluss Project at Makerere University UGA-13-0030
6 · The paper itself

Abstract

backgroundIn Uganda, the incidence and determinants of perinatal death in obstructed labour are not well documented. We determined the incidence and determinants of perinatal mortality among women with obstructed labour in Eastern Uganda.

methodsBetween July 2018 and September 2019, 584 with obstructed labour were recruited and followed up to the 7th day postnatal. Information on maternal characteristics, obstetric factors and laboratory parameters was collected. Each patient received the standard perioperative care. We used a generalized linear model for the Poisson family, with a log link and robust variance estimation to determine the association between the exposure variables and perinatal death.

resultsOf the 623 women diagnosed with obstructed labour, 584 met the eligibility criteria. There were 24 fresh still births (FSB) and 32 early neonatal deaths (ENND) giving an FSB rate of 43.8 (95% CI 28.3-64.4) deaths per 1000 total births; early neonatal death rate of 58.4 (95% CI 40.3-81.4) deaths per 1000 and an overall perinatal mortality rate of 102.2 (95% CI 79.4-130.6) deaths in the first 7 days of life. A mother being referred in active labour adjusted risk ratio of 2.84 (95% CI: 1.35-5.96) and having high blood lactate levels at recruitment adjusted risk ratio 2.71 (95% CI: 1.26-4.24) were the determinants of perinatal deaths.

conclusionsThe incidence of perinatal death was four times the regional and national average. Babies to women referred in active labour and those with high maternal blood lactate were more likely to die.

Indexed as

DeterminantsLactateObstructed labourPerinatal death

Identifiers

PMID34266492
PMCPMC8281707
OpenAlexW3181769291

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LicenceCC BY
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.