Evidence map›Paper›PMID 34266454›Full record

ArticleCritical care (London, England)2021

Longitudinal changes in compliance, oxygenation and ventilatory ratio in COVID-19 versus non-COVID-19 pulmonary acute respiratory distress syndrome.

François Beloncle, Antoine Studer, Valérie Seegers, Jean-Christophe Richard, Christophe Desprez, Nicolas Fage, Hamid Merdji, Bertrand Pavlovsky, Julie Helms, Sibylle Cunat and 5 more

Registry-linked trialAbstract readComparative Study
In one paragraph

Article in Critical care (London, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04385004 (Characterization of the Clinical, Biological and Histological Pulmonary and Renal Damage Associated With the SARS-CoV-2 Syndrome in Patients Admitted in the Intensive Care Unit), which is not on this map. Cited by 31 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04385004 unknown statusnot on this map

Characterization of the Clinical, Biological and Histological Pulmonary and Renal Damage Associated With the SARS-CoV-2 Syndrome in Patients Admitted in the Intensive Care Unit

TypeobservationalSponsorUniversity Hospital, Strasbourg, FranceRan2020 to 2020Enrolled320ConditionsAcute Respiratory Distress Syndrome
3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  14. Survival analysis of COVID-19 versus non-COVID-19 patients requiring intensive care for acute respiratory distress syndrome: An observational retrospective study.Canadian journal of respiratory therapy : CJRT = Revue canadienne de la therapie respiratoire : RCTR · 2024
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors.

François BeloncleMedical ICU, University Hospital of Angers, Vent'Lab, University of Angers, Angers, France. Francois.beloncle@univ-angers.fr.ORCID http://orcid.org/0000-0002-0590-459X
Antoine StuderMedical ICU, University Hospital of Strasbourg, University of Strasbourg, Strasbourg, France.
Valérie SeegersOncology Data Factory and Analytics, ICO Integrated Center for Oncology, Angers, France.
Jean-Christophe RichardMedical ICU, University Hospital of Angers, Vent'Lab, University of Angers, Angers, France.
Christophe DesprezMedical ICU, University Hospital of Angers, Vent'Lab, University of Angers, Angers, France.
Nicolas FageMedical ICU, University Hospital of Angers, Vent'Lab, University of Angers, Angers, France.
Hamid MerdjiMedical ICU, University Hospital of Strasbourg, University of Strasbourg, Strasbourg, France.
Bertrand PavlovskyMedical ICU, University Hospital of Angers, Vent'Lab, University of Angers, Angers, France.
Julie HelmsMedical ICU, University Hospital of Strasbourg, University of Strasbourg, Strasbourg, France.
Sibylle CunatMedical ICU, University Hospital of Strasbourg, University of Strasbourg, Strasbourg, France.
Satar MortazaMedical ICU, University Hospital of Angers, Vent'Lab, University of Angers, Angers, France.
Julien DemiselleMedical ICU, University Hospital of Angers, Vent'Lab, University of Angers, Angers, France.
Laurent BrochardKeenan Research Centre, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, Canada.
Alain MercatMedical ICU, University Hospital of Angers, Vent'Lab, University of Angers, Angers, France.
Ferhat MezianiMedical ICU, University Hospital of Strasbourg, University of Strasbourg, Strasbourg, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDifferences in physiology of ARDS have been described between COVID-19 and non-COVID-19 patients. This study aimed to compare initial values and longitudinal changes in respiratory system compliance (C

methods135 patients with COVID-19 ARDS from two centers were included in a physiological study; 767 non-COVID-19 ARDS from a clinical trial were used for the purpose of at least 1:2 matching. A propensity-matching was based on age, severity score, oxygenation, positive end-expiratory pressure (PEEP) and pulmonary cause of ARDS and allowed to include 112 COVID-19 and 198 non-COVID pulmonary ARDS.

resultsThe two groups were similar on initial oxygenation. COVID-19 patients had a higher body mass index, higher C

conclusionsFor a similar initial oxygenation, COVID-19 ARDS initially differs from classical ARDS by a higher C

trial registrationclinicaltrials.gov NCT04385004.

Indexed as

AgedBlood Gas AnalysisBody Mass IndexCOVID-19FemaleHumansIntensive Care UnitsMaleMiddle AgedPositive-Pressure RespirationPropensity ScorePulmonary Gas ExchangeRespiration, ArtificialRespiratory Distress SyndromeRespiratory Function TestsRespiratory MechanicsAcute Respiratory Distress SyndromeCovid-19Dead spaceMechanical ventilationRespiratory failureRespiratory mechanics

Identifiers

PMID34266454
PMCPMC8280689

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.