Evidence map›Paper›PMID 34266419›Full record

ReviewJournal of nanobiotechnology2021

Graphene-based nanomaterials for breast cancer treatment: promising therapeutic strategies.

Guangman Cui, Junrong Wu, Jiaying Lin, Wenjing Liu, Peixian Chen, Meng Yu, Dan Zhou, Guangyu Yao

Open access · goldAbstract readReview
In one paragraph

Review in Journal of nanobiotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 80 citations in OpenAlex.

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  12. Impact of Nanomedicine in Women's Metastatic Breast Cancer.Small (Weinheim an der Bergstrasse, Germany) · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Guangman Cui *Breast Center, Department of General Surgery, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Junrong Wu *Stomatological Hospital, Southern Medical University, Guangzhou, China.
Jiaying Lin *Breast Center, Department of General Surgery, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Wenjing LiuStomatological Hospital, Southern Medical University, Guangzhou, China.
Peixian ChenDepartment of Breast Surgery, The First People's Hospital of Foshan, Sun Yat-Sen University, Guangdong, China.
Meng YuGuangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, China.
Dan ZhouDepartment of Breast Surgery, The First People's Hospital of Foshan, Sun Yat-Sen University, Guangdong, China. 402337056@qq.com.
Guangyu YaoBreast Center, Department of General Surgery, Nanfang Hospital, Southern Medical University, Guangzhou, China. yaogy@smu.edu.cn.
Nanfang Hospital · CNSouthern Medical University · CNFirst People's Hospital of Foshan · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Breast cancer is the most common malignancy in women, and its incidence increases annually. Traditional therapies have several side effects, leading to the urgent need to explore new smart drug-delivery systems and find new therapeutic strategies. Graphene-based nanomaterials (GBNs) are potential drug carriers due to their target selectivity, easy functionalization, chemosensitization and high drug-loading capacity. Previous studies have revealed that GBNs play an important role in fighting breast cancer. Here, we have summarized the superior properties of GBNs and modifications to shape GBNs for improved function. Then, we focus on the applications of GBNs in breast cancer treatment, including drug delivery, gene therapy, phototherapy, and magnetothermal therapy (MTT), and as a platform to combine multiple therapies. Their advantages in enhancing therapeutic effects, reducing the toxicity of chemotherapeutic drugs, overcoming multidrug resistance (MDR) and inhibiting tumor metastasis are highlighted. This review aims to help evaluate GBNs as therapeutic strategies and provide additional novel ideas for their application in breast cancer therapy.

Indexed as

AnimalsBreast NeoplasmsDrug CarriersDrug Delivery SystemsDrug Resistance, MultipleDrug Resistance, NeoplasmFemaleGenetic TherapyGraphiteHumansMiceNanostructuresOptical ImagingPhototherapyDrug CarriersGraphiteBreast cancerGraphene-based nanomaterialTargetingTherapeutic strategies

Identifiers

PMID34266419
PMCPMC8281664
OpenAlexW3177620586

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.