Evidence map›Paper›PMID 34265625›Full record

ArticleJournal of neuroimmunology2021

Complex movement disorders in SARS-CoV-2 infection induced acute disseminated encephalomyelitis.

Ritwik Ghosh, Souvik Dubey, Arpan Mandal, Biman Kanti Ray, Julián Benito-León

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in Journal of neuroimmunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. SARS-CoV-2 and Environmental Changes: The Perfect Storm.Current issues in molecular biology · 2024
    Review
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Ritwik GhoshDepartment of General Medicine, Burdwan Medical College & Hospital, Burdwan, West Bengal, India.
Souvik DubeyDepartment of Neuromedicine, Bangur Institute of Neurosciences, Kolkata, India.
Arpan MandalDepartment of General Medicine, Burdwan Medical College & Hospital, Burdwan, West Bengal, India.
Biman Kanti RayDepartment of Neuromedicine, Bangur Institute of Neurosciences, Kolkata, India.
Julián Benito-LeónDepartment of Neurology, University Hospital "12 de Octubre", Madrid, Spain; Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain; Department of Medicine, Complutense University, Madrid, Spain. Electronic address: jbenitol67@gmail.com.
Burdwan Medical College & Hospital · INBangur Institute of Neurosciences · INBiomedical Research Networking Center on Neurodegenerative Diseases · ESInstitute of Neurosciences Kolkata · IN

Funding

ENVIRONMENTAL EPIDEMIOLOGY OF ESSENTIAL TREMORR01NS039422 · NINDS · YALE UNIVERSITY · PI LOUIS, ELAN D · 2000 to 2013
$7.7M
NINDS NIH HHS R01 NS039422
6 · The paper itself

Abstract

Movement disorders are extremely rare in acute disseminated encephalomyelitis (ADEM) and in the novel severe acute respiratory syndrome coronavirus (SARS-CoV-2) infection. We herein report a 34-years-old previously healthy woman who presented with a febrile illness and a constellation of movement disorders (predominantly myoclonus) followed by encephalopathy. After exclusion of common infectious, autoimmune and paraneoplastic etiologies, she was diagnosed to have COVID-19 induced ADEM, which responded to intravenous methylprednisolone and intravenous immunoglobulin. Our case adds to the tally of cases of post-SARS-CoV-2 infection related movement disorders and to the exceedingly rare list of cases in which movement disorders preceded ADEM.

Indexed as

AdultCOVID-19Encephalomyelitis, Acute DisseminatedFemaleHumansMovement DisordersAcute disseminated encephalomyelitisADEMCOVID-19Movement disordersMyoclonusSARS-CoV-2

Identifiers

PMID34265625
PMCPMC8243636
OpenAlexW3176966123

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.