Evidence map›Paper›PMID 34265354›Full record

ArticleToxicology and applied pharmacology2021

The efficacy of γ-aminobutyric acid type A receptor (GABA

Paige C Mundy, Brandon Pressly, Dennis R Carty, Bianca Yaghoobi, Heike Wulff, Pamela J Lein

Abstract read
In one paragraph

Article in Toxicology and applied pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Paige C MundyDepartment of Molecular Biosciences, University of California, School of Veterinary Medicine, Davis, CA 95616, United States. Electronic address: pacmundy@ucdavis.edu.
Brandon PresslyDepartment of Pharmacology, University of California, School of Medicine, Davis, CA 95616, United States. Electronic address: bpressly@ucdavis.edu.
Dennis R CartyDepartment of Molecular Biosciences, University of California, School of Veterinary Medicine, Davis, CA 95616, United States.
Bianca YaghoobiDepartment of Molecular Biosciences, University of California, School of Veterinary Medicine, Davis, CA 95616, United States. Electronic address: byaghoobi@ucdavis.edu.
Heike WulffDepartment of Pharmacology, University of California, School of Medicine, Davis, CA 95616, United States. Electronic address: hwulff@ucdavis.edu.
Pamela J LeinDepartment of Molecular Biosciences, University of California, School of Veterinary Medicine, Davis, CA 95616, United States. Electronic address: pjlein@ucdavis.edu.

Funding

Training and Education CoreU54NS079202 · NINDS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI LEIN, PAMELA J · 2012 to 2021
$35.7M
Identification of novel therapeutic approaches for TETS and OP intoxicationR21NS072094 · NINDS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI LEIN, PAMELA J, ROGAWSKI, MICHAEL A. · 2010 to 2011
$767k
Identifying Molecular Targets for the Proconvulsant Activity of TETSR21NS110647 · NINDS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI LEIN, PAMELA J, WULFF, HEIKE · 2019 to 2020
$414k
NINDS NIH HHS R21 NS072094NINDS NIH HHS R21 NS110647NINDS NIH HHS U54 NS079202
6 · The paper itself

Abstract

The chemical threat agent tetramethylenedisulfotetramine (TETS) is a γ-aminobutyric acid type A receptor (GABA

Indexed as

Bridged-Ring CompoundsConvulsantsAnimalsBehavior, AnimalGABA ModulatorsHypnotics and SedativesLarvaLocomotionMidazolamProtein SubunitsReceptors, GABA-ASeizuresZebrafishBridged-Ring CompoundsConvulsantsGABA ModulatorsHypnotics and SedativesMidazolamProtein SubunitsReceptors, GABA-AtetramethylenedisulfotetramineBenzodiazepineChemical Threat AgentGABA(A)RSeizuresTetramethylenedisulfotetramineZebrafish

Identifiers

PMID34265354
PMCPMC8514104

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.