Evidence map›Paper›PMID 34265141›Full record

ArticleAngewandte Chemie (International ed. in English)2021

Electrochemical Modulation of Carbon Monoxide-Mediated Cell Signaling.

Jimin Park, Joy S Zeng, Atharva Sahasrabudhe, Kyoungsuk Jin, Yoel Fink, Karthish Manthiram, Polina Anikeeva

Open access · greenAbstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Article
  3. Electrochemistry as a Tool for Redox-Based Bio-Information Processing.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Membrane-Bound Redox Enzyme CytochromeInternational journal of molecular sciences · 2024
    Article
  10. Review
  11. Review
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Jimin ParkDepartment of Materials Science and Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.ORCID 0000-0002-7935-4340
Joy S ZengDepartment of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.
Atharva SahasrabudheResearch Laboratory of Electronics and McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.
Kyoungsuk JinDepartment of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.
Yoel FinkDepartment of Materials Science and Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.
Karthish ManthiramDepartment of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.
Polina AnikeevaDepartment of Materials Science and Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.ORCID 0000-0001-6495-5197
Massachusetts Institute of Technology · USMcGovern Institute for Brain Research · US

Funding

Multi-Site Non-Invasive Magnetothermal Excitation and Inhibition of Deep Brain StructuresR01MH111872 · NIMH · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI ANIKEEVA, POLINA O, PRALLE, ARND · 2016 to 2019
$3.6M
Optogenetics to improve hand function after spinal cord injury.R01NS115025 · NINDS · UNIVERSITY OF WASHINGTON · PI ANIKEEVA, POLINA O, MORITZ, CHET T. · 2020 to 2023
$2.4M
Wireless Magnetomechanical Neuromodulation of Targeted CircuitsR01NS115576 · NINDS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI ANIKEEVA, POLINA O · 2020 to 2020
$1.6M
Hock E. Tan and K. Lisa Yang Center for Autism ResearchKwanjeong Educational FoundationMcGovern Institute for Brain Research Lore Harp McGovern graduate student fellowshipNational Science Foundation 1955628National Science Foundation Center for Neurotechnology (EEC-1028725)NIH HHS BRAIN Initiative (5-R01-MH111872, 1-R01-NS115576)NIMH NIH HHS R01 MH111872NINDS NIH HHS 1-R01-NS115025NINDS NIH HHS R01 NS115025NINDS NIH HHS R01 NS115576
6 · The paper itself

Abstract

Despite the critical role played by carbon monoxide (CO) in physiological and pathological signaling events, current approaches to deliver this messenger molecule are often accompanied by off-target effects and offer limited control over release kinetics. To address these challenges, we develop an electrochemical approach that affords on-demand release of CO through reduction of carbon dioxide (CO

Indexed as

Electrochemical TechniquesSignal TransductionCarbon MonoxideHEK293 CellsHumansCarbon Monoxidecarbon monoxidecell signalingelectrochemistryfiber drawingreceptors

Identifiers

PMID34265141
PMCPMC8405587
OpenAlexW3179499993

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.