Evidence map›Paper›PMID 34265080›Full record

ArticleJournal of neurochemistry2022

Regional and sex differences in spontaneous striatal dopamine transmission.

James N Brundage, Colin P Mason, Hillary A Wadsworth, Chris S Finuf, Josh J Nelson, P Joakim W Ronström, Sara R Jones, Cody A Siciliano, Scott C Steffensen, Jordan T Yorgason

Open access · bronzeAbstract read
In one paragraph

Article in Journal of neurochemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 33 citations in OpenAlex.

  1. Trial
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  10. Sex and estradiol effects in the rodent dorsal striatum.The European journal of neuroscience · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

James N BrundageNeuroscience Center, Brigham Young University, Provo, UT, USA.
Colin P MasonNeuroscience Center, Brigham Young University, Provo, UT, USA.
Hillary A WadsworthNeuroscience Center, Brigham Young University, Provo, UT, USA.
Chris S FinufDepartment of Psychology and Neuroscience Center, Brigham Young University, Provo, UT, USA.
Josh J NelsonNeuroscience Center, Brigham Young University, Provo, UT, USA.
P Joakim W RonströmNeuroscience Center, Brigham Young University, Provo, UT, USA.
Sara R JonesDepartment of Physiology and Pharmacology, Wake Forest School of Medicine, NC, USA.
Cody A SicilianoDepartment of Pharmacology, Vanderbilt Brain Institute, Vanderbilt Center for Addiction Research, Vanderbilt University, Nashville, TN, USA.
Scott C SteffensenDepartment of Psychology and Neuroscience Center, Brigham Young University, Provo, UT, USA.
Jordan T YorgasonNeuroscience Center, Brigham Young University, Provo, UT, USA.ORCID 0000-0002-5687-0676
Brigham Young University · USVanderbilt University · USWake Forest University · US

Funding

TROPANE EVALUATION AND GENERAL SCIENTIFIC SERVICES COREP50DA006634 · NIDA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI PORRINO, LINDA J. · 1991 to 2019
$30.8M
Wake Forest Translational Alcohol Research Center (WF-TARC)P50AA026117 · NIAAA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI Jeffrey L. Weiner · 2018 to 2026
$16.2M
MULTI-DISCIPLINARY TRAINING IN THE BIOLOGY OF ALCOHOLISMT32AA007565 · NIAAA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI BRIAN A MCCOOL · 1994 to 2026
$10.1M
Role of Kappa Opioid Receptors in Maladaptive Catecholamine Responses to Stress and Alcohol ExposureU01AA014091 · NIAAA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI Katherine Mercedes Holleran, SARA RAULERSON JONES · 2003 to 2026
$7.7M
Biased Kappa Opioid Agonists as Non-addictive AnalgesicsR01DA048490 · NIDA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI JONES, SARA RAULERSON, MARTIN, THOMAS JEFFREY · 2019 to 2023
$3.4M
Mesocortical neuromodulation in punishment-resistant alcohol drinkingR01AA030115 · NIAAA · VANDERBILT UNIVERSITY · PI Cody Siciliano · 2022 to 2026
$2.1M
Nicotine and Alcohol Co-DependenceR01DA035958 · NIDA · BRIGHAM YOUNG UNIVERSITY · PI STEFFENSEN, SCOTT C · 2014 to 2018
$2.0M
8/8: INIA Stress and Chronic Alcohol Interactions: Cross-species plasticity signatures of alcohol and stressU01AA029971 · NIAAA · VANDERBILT UNIVERSITY · PI Cody Siciliano · 2022 to 2026
$2.0M
Ethanol Dependence Induced Changes in Dopamine Signaling in Basolateral AmygdalaR01AA023999 · NIAAA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI JONES, SARA RAULERSON, MCCOOL, BRIAN A · 2015 to 2019
$1.8M
The Neurobiology of Drug AbuseT32DA041349 · NIDA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI SARA RAULERSON JONES · 2017 to 2026
$1.8M
Neuroplasticity with alcohol dependenceR01AA020919 · NIAAA · BRIGHAM YOUNG UNIVERSITY · PI STEFFENSEN, SCOTT C · 2012 to 2016
$1.5M
Defining the role of cortical circuit dynamics in learning and addictionR00DA045103 · NIDA · VANDERBILT UNIVERSITY · PI SICILIANO, CODY · 2020 to 2022
$764k
NIAAA NIH HHS P50 AA026117NIAAA NIH HHS R01 AA020919NIAAA NIH HHS R01 AA030115NIAAA NIH HHS T32 AA007565NIAAA NIH HHS U01 AA014091NIAAA NIH HHS U01 AA029971NIDA NIH HHS F32 DA040409NIDA NIH HHS K99 DA045103NIDA NIH HHS P50 DA006634NIDA NIH HHS R00 DA045103NIDA NIH HHS R01 DA035958NIDA NIH HHS R01 DA048490NIDA NIH HHS T32 DA041349
6 · The paper itself

Abstract

Striatal dopamine release is key for learning and motivation and is composed of subregions including the dorsal striatum (DS), nucleus accumbens core, and the nucleus accumbens shell. Spontaneously occurring dopamine release was compared across these subregions. Dopamine release/uptake dynamics differ across striatal subregions, with dopamine transient release amplitude and release frequency greatest in male mice, and the largest signals observed in the DS. Surprisingly, female mice exhibited little regional differences in dopamine release for DS and nucleus accumbens core regions, but lower release in the nucleus accumbens shell. Blocking voltage-gated K

Indexed as

CocaineDopamine4-AminopyridineAnimalsCorpus StriatumDopamine AntagonistsDopamine Plasma Membrane Transport ProteinsFemaleMaleMiceNucleus AccumbensSex Characteristics4-AminopyridineCocaineDopamineDopamine AntagonistsDopamine Plasma Membrane Transport ProteinsaccumbenscocainedopamineKv channelssex differencesstriatum

Identifiers

PMID34265080
PMCPMC10044475
OpenAlexW3182067673

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.