Evidence map›Paper›PMID 34265067›Full record

ReviewEndocrinology2021

Ventromedial Nucleus of the Hypothalamus Neurons Under the Magnifying Glass.

Tansi Khodai, Simon M Luckman

Open access · hybridAbstract readReview
In one paragraph

Review in Endocrinology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 58 citations in OpenAlex.

  1. Article
  2. Article
  3. Projection-defined hypothalamic outputs differentially regulate thermogenesis and lipolysis.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  4. Article
  5. Article
  6. Identification of a neural basis for anorexia nervosa.bioRxiv : the preprint server for biology · 2026
    Article
  7. Sex differences in the neural circuitry of aggression.bioRxiv : the preprint server for biology · 2025
    Article
  8. Article
  9. Role of Hypothalamic CRH Neurons in Regulating the Impact of Stress on Memory and Sleep.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Tansi KhodaiFaculty of Biology, Medicine and Health, The University of Manchester, Oxford Road, Manchester, UK.
Simon M LuckmanFaculty of Biology, Medicine and Health, The University of Manchester, Oxford Road, Manchester, UK.ORCID 0000-0003-2398-6389
University of Manchester · GB

Funding

Biotechnology and Biological Sciences Research Council NEU15392Medical Research Council MR/R002991/1
6 · The paper itself

Abstract

The ventromedial nucleus of the hypothalamus (VMH) is a complex brain structure that is integral to many neuroendocrine functions, including glucose regulation, thermogenesis, and appetitive, social, and sexual behaviors. As such, it is of little surprise that the nucleus is under intensive investigation to decipher the mechanisms which underlie these diverse roles. Developments in genetic and investigative tools, for example the targeting of steroidogenic factor-1-expressing neurons, have allowed us to take a closer look at the VMH, its connections, and how it affects competing behaviors. In the current review, we aim to integrate recent findings into the literature and contemplate the conclusions that can be drawn.

Indexed as

AggressionAnimalsBlood GlucoseBody WeightEatingEnergy MetabolismFeeding BehaviorFemaleFluorescenceGlucoseHomeostasisHumansHypothalamusMaleMiceNeuronsBlood GlucoseGlucoseSteroidogenic Factor 1body weightcounter-regulatory responseglucosesexual dimorphismVMH

Identifiers

PMID34265067
PMCPMC8331052
OpenAlexW3179553694

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.