ArticlePLoS genetics2021
Identification of a gustatory receptor tuned to sinigrin in the cabbage butterfly Pieris rapae.
Article in PLoS genetics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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27 citing papers in PubMed, 66 citations in OpenAlex.
- Early hexapod genomes reveal the deep origin of insect gustatory and odorant receptors.Nature communications · 2026Article
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- The lepidopteran analyst: how caterpillars, moths and butterflies encode taste identity and valence.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2026Review
- Expanding the sensory horizon: chemosensory receptors beyond traditional olfactory and taste organs in insects.Science China. Life sciences · 2026Review
- Metabolomic analysis of a core collection of Brassica rapa and Brassica oleracea unveils unexpected chemical diversity with potential applications in chemical ecology and breeding.BMC plant biology · 2026Article
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- Analysis of antennal transcriptome and gustatory receptor genes in Apis cerana cerana collecting pollens from different nectar source plants.BMC genomics · 2025Article
- Natural Resistance to and Attraction of the Cabbage Root Fly (Journal of agricultural and food chemistry · 2025Article
- Alternative Splicing in TRPA1 Drives Sensory Adaptation to Electrophiles in Drosophilids.bioRxiv : the preprint server for biology · 2025Article
- A structural perspective on insect gustatory receptors.Chemical senses · 2025Review
- Molecular Functions and Physiological Roles of Gustatory Receptors of the SilkwormInternational journal of molecular sciences · 2024Review
- Olfactory learning inProceedings. Biological sciences · 2024Article
- Chemosensory detection of glucosinolates as token stimuli for specialist insects on brassicaceous plants: discovery and impact.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2024Review
- Taste evolution in an herbivorous drosophilid.bioRxiv : the preprint server for biology · 2024Article
- Analysis of Genes Associated with Feeding Preference and Detoxification in Various Developmental Stages ofInsects · 2024Article
- Caterpillar Responses to Gustatory Stimuli in Potato Tuber Moths: Electrophysiological and Behavioral Insights.Life (Basel, Switzerland) · 2023Article
- Plant Glucosinolate Content and Host-Plant Preference and Suitability in the Small White Butterfly (Lepidoptera: Pieridae) and Comparison with Another Specialist Lepidopteran.Plants (Basel, Switzerland) · 2023Article
- SympatricFrontiers in cellular neuroscience · 2023Article
- Identification and expression analysis of chemosensory receptors in the tarsi of fall armyworm,Frontiers in physiology · 2023Article
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Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Glucosinolates are token stimuli in host selection of many crucifer specialist insects, but the underlying molecular basis for host selection in these insects remains enigmatic. Using a combination of behavioral, electrophysiological, and molecular methods, we investigate glucosinolate receptors in the cabbage butterfly Pieris rapae. Sinigrin, as a potent feeding stimulant, elicited activity in larval maxillary lateral sensilla styloconica, as well as in adult medial tarsal sensilla. Two P. rapae gustatory receptor genes PrapGr28 and PrapGr15 were identified with high expression in female tarsi, and the subsequent functional analyses showed that Xenopus oocytes only expressing PrapGr28 had specific responses to sinigrin; when ectopically expressed in Drosophila sugar sensing neurons, PrapGr28 conferred sinigrin sensitivity to these neurons. RNA interference experiments further showed that knockdown of PrapGr28 reduced the sensitivity of adult medial tarsal sensilla to sinigrin. Taken together, we conclude that PrapGr28 is a gustatory receptor tuned to sinigrin in P. rapae, which paves the way for revealing the molecular basis of the relationships between crucifer plants and their specialist insects.
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