Evidence map›Paper›PMID 34264525›Full record

ArticleAmerican journal of hematology2021

An artificial intelligence-assisted diagnostic platform for rapid near-patient hematology.

Neta Bachar, Dana Benbassat, David Brailovsky, Yochay Eshel, Dan Glück, Daniel Levner, Sarah Levy, Sharon Pecker, Evgeny Yurkovsky, Amir Zait and 3 more

Open access · hybridAbstract readValidation Study
In one paragraph

Article in American journal of hematology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 45 citations in OpenAlex.

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  12. Artificial Intelligence in Point-of-Care Testing.Annals of laboratory medicine · 2023
    Review
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  16. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 2 countries.

Neta BacharS.D. Sight Diagnostics LTD, Tel Aviv-Jaffa, Israel.
Dana BenbassatS.D. Sight Diagnostics LTD, Tel Aviv-Jaffa, Israel.
David BrailovskyS.D. Sight Diagnostics LTD, Tel Aviv-Jaffa, Israel.
Yochay EshelS.D. Sight Diagnostics LTD, Tel Aviv-Jaffa, Israel.
Dan GlückS.D. Sight Diagnostics LTD, Tel Aviv-Jaffa, Israel.
Daniel LevnerS.D. Sight Diagnostics LTD, Tel Aviv-Jaffa, Israel.
Sarah LevyS.D. Sight Diagnostics LTD, Tel Aviv-Jaffa, Israel.
Sharon PeckerS.D. Sight Diagnostics LTD, Tel Aviv-Jaffa, Israel.
Evgeny YurkovskyS.D. Sight Diagnostics LTD, Tel Aviv-Jaffa, Israel.
Amir ZaitS.D. Sight Diagnostics LTD, Tel Aviv-Jaffa, Israel.
Cordelia SeverTriCore Reference Laboratories, Albuquerque, New Mexico, USA.
Alexander KratzDepartment of Pathology and Cell Biology, Columbia University College of Physicians and Surgeons, New York, New York, USA.
Carlo BrugnaraDepartment of Laboratory Medicine, Boston Children's Hospital, Boston, Massachusetts, USA.ORCID 0000-0001-8192-8713
Pronto Diagnostics (Israel) · ILApplied Research Associates (United States) · USBoston Children's Hospital · USNewYork–Presbyterian Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hematology analyzers capable of performing complete blood count (CBC) have lagged in their prevalence at the point-of-care. Sight OLO (Sight Diagnostics, Israel) is a novel hematological platform which provides a 19-parameter, five-part differential CBC, and is designed to address the limitations in current point-of-care hematology analyzers using recent advances in artificial intelligence (AI) and computer vision. Accuracy, repeatability, and flagging capabilities of OLO were compared with the Sysmex XN-Series System (Sysmex, Japan). Matrix studies compared performance using venous, capillary and direct-from-fingerprick blood samples. Regression analysis shows strong concordance between OLO and the Sysmex XN, demonstrating that OLO performs with high accuracy for all CBC parameters. High repeatability and reproducibility were demonstrated for most of the testing parameters. The analytical performance of the OLO hematology analyzer was validated in a multicenter clinical laboratory setting, demonstrating its accuracy and comparability to clinical laboratory-based hematology analyzers. Furthermore, the study demonstrated the validity of CBC analysis of samples collected directly from fingerpricks.

Indexed as

Artificial IntelligencePoint-of-Care SystemsBlood Cell CountEquipment DesignHumansReproducibility of Results

Identifiers

PMID34264525
PMCPMC9290600
OpenAlexW3158050822

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.