Evidence map›Paper›PMID 34264467›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2021

A Rat Model of Orthopedic Implant-Associated Infection for Identification of Staphylococcal Biofilm Proteins.

Mei G Lei, Ravi Kr Gupta, Chia Y Lee

Abstract read
PubMed Publisher
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
4.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Mei G LeiDepartment of Microbiology and Immunology, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
Ravi Kr GuptaDepartment of Microbiology and Immunology, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
Chia Y LeeDepartment of Microbiology and Immunology, University of Arkansas for Medical Sciences, Little Rock, AR, USA. CLee2@uams.edu.
University of Arkansas for Medical Sciences · USBabasaheb Bhimrao Ambedkar University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Secreted bacterial proteins are difficult to identify directly from an infection site due to a limited amount of bacteria and presence of a large quantity of host proteins. Here we describe a rat model of orthopedic implant that allows us to harvest bacterial biofilm materials sufficient for identification of bacterial proteins in the biofilm matrix by liquid chromatography-tandem MS (GeLC-MS/MS) analysis.

Indexed as

AnimalsBacterial ProteinsBiofilmsChromatography, LiquidDisease Models, AnimalMaleProstheses and ImplantsProsthesis-Related InfectionsRatsStaphylococcal InfectionsStaphylococcus aureusTandem Mass SpectrometryBacterial ProteinsBacteriaBiofilm matrix proteinsOrthopedic implant-associated infectionProteomicsStaphylococcus aureus

Identifiers

PMID34264467
OpenAlexW3178426723

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.