Evidence map›Paper›PMID 34264444›Full record

SynthesisActa parasitologica2022

Echinococcus granulosus sensu lato Genotypes in Different Hosts Worldwide: A Systematic Review.

Carlos Manterola, Armando Totomoch-Serra, Claudio Rojas, Ángela L Riffo-Campos, Nayely García-Méndez

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Acta parasitologica, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. Global distribution ofParasitology · 2022
    Pooled it
  2. Molecular characterization ofOpen veterinary journal · 2026
    Article
  3. Observational
  4. Review
  5. Article
  6. Article
  7. Five-Year Slaughterhouse-Based Surveillance ofPathogens (Basel, Switzerland) · 2025
    Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Molecular characterization ofJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2024
    Article
  16. Identification and genotyping ofParasite epidemiology and control · 2024
    Article
  17. Article
  18. Article
  19. Genetic diversity ofVeterinary world · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 2 countries.

Carlos ManterolaPhD Program in Medical Sciences and CEMyQ, Universidad de La Frontera, Manuel Montt 112, Office 408, Temuco, Chile. carlos.manterola@ufrontera.cl.ORCID http://orcid.org/0000-0001-9213-2905
Armando Totomoch-SerraPhD Program in Medical Sciences and CEMyQ, Universidad de La Frontera, Manuel Montt 112, Office 408, Temuco, Chile.
Claudio RojasPhD Program in Medical Sciences and CEMyQ, Universidad de La Frontera, Manuel Montt 112, Office 408, Temuco, Chile.
Ángela L Riffo-CamposPhD Program in Medical Sciences and CEMyQ, Universidad de La Frontera, Manuel Montt 112, Office 408, Temuco, Chile.
Nayely García-MéndezPhD Program in Medical Sciences and CEMyQ, Universidad de La Frontera, Manuel Montt 112, Office 408, Temuco, Chile.
Universidad de La Frontera · CL

Funding

Universidad de La Frontera DIUFRO DI19-0030
6 · The paper itself

Abstract

introductionThe aim of this study was to develop a synthesis of the evidence available regarding verified E. granulosus sensu lato (s.l.) genotypes in different species worldwide. MATERIAL AND

methodsA systematic review was performed including studies concerning genotypes of E. granulosus s.l. without language or genotyped method restriction, published between 1990 and 2020. A systematic search was carried out in Trip Database, BIREME, SciELO, LILACS, IBECS, PAHO-WHO, EMBASE, PubMed, Scopus, and WoS. Variables of interest were year of publication, country, number of samples, and hosts; genotypes, molecular marker, haplotypes and molecular biology techniques used. Descriptive statistics were applied.

results2411 articles were analyzed, however 135 met the selection criteria, representing 8643 liver and lung samples. Of the samples selected 24% were human, the remaining samples pertained to non-human animal hosts; cattle and sheep prevailed with 28.6% and 26.6% of the studied samples, respectively. The reported evidence is mainly from Iran, Turkey, Argentina, China and Chile; with 50, 11, 6, 6 and 5 studies, respectively, published between 1992 and 2020 [most frequently during 2015-2020 (76/135 studies; 56.3%)]. The mitochondrial gene cox1 was generally sequenced and informative (91.8%). Genotypes most frequently identified were E. granulosus sensu stricto (s.s.) (83.2%).

conclusionsBased on this overall evidence, it can be concluded that publications related to genotypes of E. granulosus s.l. are heterogeneous. E. granulosus ss accounts for the vast majority of the global burden of E. granulosus s.l. worldwide. Further studies including larger number of cases and adequate internal validity are required to specify the distribution of genotypes in various host species.

trial registrationPROSPERO CRD42018099827.

Indexed as

EchinococcosisEchinococcus granulosusAnimalsCattleGenes, MitochondrialGenotypeHumansSheepEchinococcosisEchinococcus granulosusGenesGenotypeSystematic review

Identifiers

PMID34264444
OpenAlexW3182933939

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.