Evidence map›Paper›PMID 34264401›Full record

ArticleEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2022

Impact of a 4-year antimicrobial stewardship program implemented in a Greek tertiary hospital.

Konstantina Chrysou, Olympia Zarkotou, Sofia Kalofolia, Panagiota Papagiannakopoulou, Vasiliki Mamali, Georgios Chrysos, Katina Themeli-Digalaki, Nikolaos Sypsas, Athanasios Tsakris, Spyros Pournaras

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In one paragraph

Article in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Antibiotic Stewardship in Surgical Departments.Antibiotics (Basel, Switzerland) · 2024
    Review
  4. Review
  5. Carbapenem-ResistantMicroorganisms · 2023
    Article
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Konstantina ChrysouDepartment of Microbiology, National and Kapodistrian University of Athens, Athens, Greece.
Olympia ZarkotouDepartment of Clinical Microbiology, Tzaneio General Hospital of Piraeus, Athens, Greece.
Sofia KalofoliaHospital Pharmacy, Tzaneio General Hospital of Piraeus, Athens, Greece.
Panagiota PapagiannakopoulouDepartment of Clinical Microbiology, Tzaneio General Hospital of Piraeus, Athens, Greece.
Vasiliki MamaliDepartment of Clinical Microbiology, Tzaneio General Hospital of Piraeus, Athens, Greece.
Georgios Chrysos2nd Department of Medicine and Infectious Disease Unit, Tzaneio General Hospital of Piraeus, Athens, Greece.
Katina Themeli-DigalakiDepartment of Clinical Microbiology, Tzaneio General Hospital of Piraeus, Athens, Greece.
Nikolaos SypsasGeneral Hospital of Athens "Laiko", National and Kapodistrian University of Athens, Athens, Greece.
Athanasios TsakrisDepartment of Microbiology, National and Kapodistrian University of Athens, Athens, Greece.
Spyros PournarasDepartment of Microbiology, National and Kapodistrian University of Athens, Athens, Greece. spournaras@med.uoa.gr.ORCID http://orcid.org/0000-0002-6298-9577

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to investigate the effects of a 4-year antibiotic stewardship program (ASP) in a tertiary hospital. We monitored data for 2015 (pre-intervention) and 2016-2019 (post-intervention) about antibiotic consumption (DDD/100 bed days), Clostridioides difficile infections (CDIs), resistance rates, length of stay (LOS), and annual antibiotic costs. Significant reductions were observed for total antibiotics/colistin/carbapenems/quinolones/tigecycline consumption and resistance rates of Pseudomonas aeruginosa, Klebsiella pneumoniae, and vancomycin-resistant enterococci. Considerable reductions occurred for LOS (4.18 [2015]/3.0 [2019] days), CDIs (1.47 [2015]/0.86 [2019] per 1000 patients), antibiotic cost/patient (39.45€ [2015]/23.69€ [2019]). The ASP was successful in reducing antibiotic consumption, antibiotic costs, length of hospital stay, and CDIs.

Indexed as

Anti-Bacterial AgentsAntimicrobial StewardshipBacteriaBacterial InfectionsDrug Resistance, BacterialGreeceHumansProspective StudiesTertiary Care CentersAnti-Bacterial AgentsAntibiotic consumptionAntibiotic costsAntimicrobial stewardshipClostridioides difficile infectionsLength of hospital stay

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.