Evidence map›Paper›PMID 34263712›Full record

ReviewExpert review of clinical immunology2021

Pathological mechanisms of abnormal iron metabolism and mitochondrial dysfunction in systemic lupus erythematosus.

Chris Wincup, Natalie Sawford, Anisur Rahman

Open access · bronzeAbstract readReview
In one paragraph

Review in Expert review of clinical immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 39 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. NPC1L1, stabilized by PABPC1/IGF2BP1, accelerates atherosclerosis by enhancing CYP11A1-mediated mitophagy and ferroptosis.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2026
    Article
  7. Review
  8. Review
  9. Trace Elements-Role in Joint Function and Impact on Joint Diseases.International journal of molecular sciences · 2025
    Review
  10. Iron metabolism in rheumatic diseases.Journal of translational autoimmunity · 2025
    Review
  11. Article
  12. Article
  13. Review
  14. Review
  15. Review
  16. Article
  17. Frequency Evaluation of theInternational journal of molecular sciences · 2023
    Article
  18. Endosome Traffic Modulates Pro-Inflammatory Signal Transduction in CD4International journal of molecular sciences · 2023
    Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Chris WincupDepartment of Rheumatology, Division of Medicine, University College London, London, UK.
Natalie SawfordDepartment of Rheumatology, Division of Medicine, University College London, London, UK.
Anisur RahmanDepartment of Rheumatology, Division of Medicine, University College London, London, UK.
University College London · GB

Funding

Versus Arthritis 21992
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

IronLupus Erythematosus, SystemicAutoantibodiesHumansMitochondriaOxidative StressAutoantibodiesIronFerroptosisfunctional iron deficiencyimmunometabolismIronmitochondriasystemic lupus erythematosus

Identifiers

PMID34263712
PMCPMC8452144
OpenAlexW3183014205

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.