Evidence map›Paper›PMID 34263665›Full record

ArticleFuture oncology (London, England)2021

Trastuzumab deruxtecan in previously treated HER2-positive metastatic breast cancer: Plain language summary of the DESTINY-Breast01 study.

Shanu Modi

Open access · hybridAbstract readCommentPatient Education Handout
PubMed Publisher
In one paragraph

Article in Future oncology (London, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 28 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. HER-2 SMASH.Cancer chemotherapy and pharmacology · 2024
    Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. An Insight into Molecular Targets of Breast Cancer Brain Metastasis.International journal of molecular sciences · 2022
    Review
  13. Article
  14. Article
  15. Molecular Landscape ofPathology oncology research : POR · 2022
    Article
  16. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Shanu ModiMemorial Sloan Kettering Cancer Center, New York, USA.
Memorial Sloan Kettering Cancer Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This is a summary of the article discussing the results of the DESTINY-Breast01 study originally published in the

Indexed as

Breast NeoplasmsAdultCamptothecinErb-b2 Receptor Tyrosine KinasesFemaleHumansImmunoconjugatesLanguageTrastuzumabCamptothecinErb-b2 Receptor Tyrosine KinasesImmunoconjugatesTrastuzumabtrastuzumab deruxtecanbreast cancerclinical trialDESTINY-Breast01ENHERTUHER2 positiveHER2-positivelay summarymetastatic breast cancerplain language summarytrastuzumab deruxtecan

Identifiers

PMID34263665
OpenAlexW3180471575

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.