Evidence map›Paper›PMID 34263419›Full record

ArticleCardiovascular engineering and technology2022

Importance of Preserved Tricuspid Valve Function for Effective Soft Robotic Augmentation of the Right Ventricle in Cases of Elevated Pulmonary Artery Pressure.

Isaac Wamala, Christopher J Payne, Mossab Y Saeed, Daniel Bautista-Salinas, David Van Story, Thomas Thalhofer, Steven J Staffa, Sunil J Ghelani, Pedro J Del Nido, Conor J Walsh and 1 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cardiovascular engineering and technology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 92% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Isaac WamalaDepartment of Cardiac Surgery, Harvard Medical School, Boston Children's Hospital, 300 Longwood Ave, Boston, MA, 02115, USA. Wamala@dhzb.de.ORCID 0000-0001-8030-9283
Christopher J PayneWyss Institute for Biologically Inspired Engineering, Boston, USA.
Mossab Y SaeedDepartment of Cardiac Surgery, Harvard Medical School, Boston Children's Hospital, 300 Longwood Ave, Boston, MA, 02115, USA.
Daniel Bautista-SalinasDepartment of Cardiac Surgery, Harvard Medical School, Boston Children's Hospital, 300 Longwood Ave, Boston, MA, 02115, USA.
David Van StoryDepartment of Cardiac Surgery, Harvard Medical School, Boston Children's Hospital, 300 Longwood Ave, Boston, MA, 02115, USA.
Thomas ThalhoferFraunhofer EMFT, Munich, Germany.
Steven J StaffaDepartment of Anesthesiology, Critical Care and Pain Medicine, Boston Children's Hospital, Boston, USA.
Sunil J GhelaniDepartment of Cardiology, Boston Children's Hospital, Boston, MA, USA.
Pedro J Del NidoDepartment of Cardiac Surgery, Harvard Medical School, Boston Children's Hospital, 300 Longwood Ave, Boston, MA, 02115, USA.
Conor J WalshWyss Institute for Biologically Inspired Engineering, Boston, USA.
Nikolay V VasilyevDepartment of Cardiac Surgery, Harvard Medical School, Boston Children's Hospital, 300 Longwood Ave, Boston, MA, 02115, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeIn clinical practice, many patients with right heart failure (RHF) have elevated pulmonary artery pressures and increased afterload on the right ventricle (RV). In this study, we evaluated the feasibility of RV augmentation using a soft robotic right ventricular assist device (SRVAD), in cases of increased RV afterload.

methodsIn nine Yorkshire swine of 65-80 kg, a pulmonary artery band was placed to cause RHF and maintained in place to simulate an ongoing elevated afterload on the RV. The SRVAD was actuated in synchrony with the ventricle to augment native RV output for up to one hour. Hemodynamic parameters during SRVAD actuation were compared to baseline and RHF levels.

resultsMedian RV cardiac index (CI) was 1.43 (IQR, 1.37-1.80) L/min/m

conclusionsShort-term augmentation of RV function using SRVAD is feasible even in cases of elevated RV afterload. Moderate or severe tricuspid regurgitation were associated with reduced device effectiveness.

Indexed as

Heart FailureRoboticsTricuspid Valve InsufficiencyAnimalsHeart VentriclesHumansPulmonary ArterySwineTricuspid ValveElevated pulmonary artery pressureRight heart failureSoft robotic ventricular assist device

Identifiers

PMID34263419
PMCPMC8888489
OpenAlexW3182807770

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.