Evidence map›Paper›PMID 34263346›Full record

ArticleAnalytical and bioanalytical chemistry2022

3D-printed microchip electrophoresis device containing spiral electrodes for integrated capacitively coupled contactless conductivity detection.

Brenda M C Costa, Aline G Coelho, Michael J Beauchamp, Jacob B Nielsen, Gregory P Nordin, Adam T Woolley, José A F da Silva

Abstract read
In one paragraph

Article in Analytical and bioanalytical chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Advancement of microchip electrophoresis coupled with capacitively coupled contactless conductivity detection-from design to application (2018-2024).Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2025
    Review
  5. 3D printed microfluidic devices with electrodes for electrochemical analysis.Analytical methods : advancing methods and applications · 2024
    Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Brenda M C CostaChemistry Institute, State University of Campinas, Campinas, SP, 13083-861, Brazil.
Aline G CoelhoChemistry Institute, State University of Campinas, Campinas, SP, 13083-861, Brazil.
Michael J BeauchampDepartment of Chemistry and Biochemistry, Brigham Young University, Provo, UT, 84602, USA.
Jacob B NielsenDepartment of Chemistry and Biochemistry, Brigham Young University, Provo, UT, 84602, USA.
Gregory P NordinDepartment of Electrical and Computer Engineering, Brigham Young University, Provo, UT, 84602, USA.
Adam T WoolleyDepartment of Chemistry and Biochemistry, Brigham Young University, Provo, UT, 84602, USA.
José A F da SilvaChemistry Institute, State University of Campinas, Campinas, SP, 13083-861, Brazil. fracassi@unicamp.br.ORCID http://orcid.org/0000-0001-9522-6181

Funding

High Density 3D Printed Microfluidics With Open Source Resins for Biomedical ApplicationsR15GM123405 · NIGMS · BRIGHAM YOUNG UNIVERSITY · PI NORDIN, GREGORY P. · 2017 to 2023
$1.3M
3D-Printed Integrated Microfluidic Devices for Preterm Birth Biomarker AnalysisR01EB027096 · NIBIB · BRIGHAM YOUNG UNIVERSITY · PI WOOLLEY, ADAM THOMAS · 2018 to 2021
$1.1M
Conselho Nacional de Desenvolvimento Científico e Tecnológico 465389/2014-7Fundação de Amparo à Pesquisa do Estado de São Paulo 2018/06478-3NIBIB NIH HHS R01 EB027096NIGMS NIH HHS R15 GM123405NIH HHS R15GM123405
6 · The paper itself

Abstract

In this work, we demonstrate for the first time the design and fabrication of microchip electrophoresis devices containing cross-shaped channels and spiral electrodes around the separation channel for microchip electrophoresis and capacitively coupled contactless conductivity detection. The whole device was prepared in a digital light processing-based 3D printer in poly(ethylene glycol) diacrylate resin. Outstanding X-Y resolution of the customized 3D printer ensured the fabrication of 40-μm cross section channels. The spiral channels were filled with melted gallium to form conductive electrodes around the separation channel. We demonstrate the applicability of the device on the separation of sodium, potassium, and lithium cations by microchip electrophoresis. Graphical abstract.

Indexed as

3D printingLiquid metal electrodesMicrochip electrophoresis

Identifiers

PMID34263346
PMCPMC8748415

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.