Evidence map›Paper›PMID 34263258›Full record

ArticleAdvances in geriatric medicine and research2021

Hospitalized Older Patients with

Jae Hyun Shin, Rachel Ann Hays, Cirle Alcantara Warren

Open access · diamondAbstract read
In one paragraph

Article in Advances in geriatric medicine and research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 60% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Jae Hyun ShinDivision of Infectious Diseases and International Health, Department of Medicine, School of Medicine, University of Virginia, Charlottesville, VA 22903, USA.
Rachel Ann HaysDivision of Gastroenterology and Hepatology, Department of Medicine, School of Medicine, University of Virginia, Charlottesville, VA 22903, USA.
Cirle Alcantara WarrenDivision of Infectious Diseases and International Health, Department of Medicine, School of Medicine, University of Virginia, Charlottesville, VA 22903, USA.
University of Virginia Health System · USUniversity of Virginia · US

Funding

Alanyl-glutamine supplementation of standard treatment for C. difficile infectionR01AI145322 · NIAID · UNIVERSITY OF VIRGINIA · PI WARREN, CIRLE ALCANTARA · 2020 to 2024
$4.0M
Aging and Clostridium difficile infection: interplay of microbiota and host responseK08AG064151 · NIA · UNIVERSITY OF VIRGINIA · PI SHIN, JAE HYUN · 2019 to 2023
$801k
NIAID NIH HHS R01 AI145322NIA NIH HHS K08 AG064151
6 · The paper itself

Abstract

backgroundOptions for

methodsElectronic medical records of patients who received FMT inpatient for refractory CDI were reviewed as part of quality improvement efforts to evaluate safety and efficacy of FMT in inpatient setting.

resultsBetween July 2014 and December 2019, 9 patients (age 60-96) received FMT for CDI as inpatient for refractory or fulminant CDI. Most (7 of 9) of these patients had pseudomembranous colitis and underwent multiple FMTs (mean 2.15, range 1 to 3). Five patients had complete resolution and one patient had diarrhea that was

conclusionsThis study shows moderate efficacy of FMT for treatment of refractory CDI although multiple FMT treatment may need to be administered in the presence of pseudomembranous colitis. Inpatient FMT may be an alternative strategy for managing refractory CDI in this population of patients who may not have any effective medical treatment available.

Indexed as

Clostridioides difficilefecal microbiota transplantfulminant C. difficilerefractory C. difficile

Identifiers

PMID34263258
PMCPMC8277114
OpenAlexW3157571269

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.