Evidence map›Paper›PMID 34263170›Full record

ArticleRSC medicinal chemistry2021

Amino alcohol acrylonitriles as broad spectrum and tumour selective cytotoxic agents.

Jennifer R Baker, Cecilia C Russell, Jayne Gilbert, Adam McCluskey, Jennette A Sakoff

Open access · greenAbstract read
In one paragraph

Article in RSC medicinal chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

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  5. Crystal structure and Hirshfeld surface analysis of 1-(Acta crystallographica. Section E, Crystallographic communications · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 3 countries.

Jennifer R BakerChemistry, School of Environmental & Life Sciences, The University of Newcastle, University Drive Callaghan NSW 2308 Australia Jennifer.R.Baker@newcastle.edu.au.ORCID https://orcid.org/0000-0002-9560-301X
Cecilia C RussellChemistry, School of Environmental & Life Sciences, The University of Newcastle, University Drive Callaghan NSW 2308 Australia Jennifer.R.Baker@newcastle.edu.au.ORCID https://orcid.org/0000-0001-8401-5856
Jayne GilbertExperimental Therapeutics Group, Department of Medical Oncology, Calvary Mater Newcastle Hospital Edith Street Waratah NSW 2298 Australia.ORCID https://orcid.org/0000-0001-5034-386X
Adam McCluskeyChemistry, School of Environmental & Life Sciences, The University of Newcastle, University Drive Callaghan NSW 2308 Australia Jennifer.R.Baker@newcastle.edu.au.ORCID https://orcid.org/0000-0001-7125-863X
Jennette A SakoffExperimental Therapeutics Group, Department of Medical Oncology, Calvary Mater Newcastle Hospital Edith Street Waratah NSW 2298 Australia.ORCID https://orcid.org/0000-0002-7009-5792
Callaghan Innovation · NZCalvary Mater Newcastle Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We have identified specific dichlorophenylacrylonitriles as lead compounds in the development of novel anticancer compounds, notably, (

Identifiers

PMID34263170
PMCPMC8223738
OpenAlexW3135190594

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.