Evidence map›Paper›PMID 34263152›Full record

ArticleEuropean journal of breast health2021

Evaluation of Three-Dimensional Conformal Radiotherapy and Intensity Modulated Radiotherapy Techniques for Left Breast Post-Mastectomy Patients: Our Experience in Nigerian Sovereign Investment Authority-Lagos University Teaching Hospital Cancer Center, South-West Nigeria.

Samuel Adeneye, Michael Akpochafor, Bolanle Adegboyega, Adewumi Alabi, Nusirat Adedewe, Adedayo Joseph, Omolara Fatiregun, Akintayo Omojola, Abe Adebayo, Esther Oluwadara

Abstract read
In one paragraph

Article in European journal of breast health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Radiation Therapy for Breast Cancer in Africa.Advances in radiation oncology · 2024
    Review
  5. Article
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Samuel AdeneyeDepartment of Radiation Biology, Division of Radiotherapy and Radiodiagnosis, College of Medicine, University of Lagos/NSIA-LUTH Cancer Centre, Lagos, Nigeria.ORCID https://orcid.org/0000-0003-3239-2785
Michael AkpochaforDepartment of Radiation Biology, Division of Radiotherapy and Radiodiagnosis, College of Medicine, University of Lagos/NSIA-LUTH Cancer Centre, Lagos, Nigeria.ORCID https://orcid.org/0000-0001-5903-676X
Bolanle AdegboyegaDepartment of Radiotherapy, Lagos University Teaching Hospital, Lagos, Nigeria.ORCID https://orcid.org/0000-0001-5208-8073
Adewumi AlabiDepartment of Radiation Biology, Division of Radiotherapy and Radiodiagnosis, College of Medicine, University of Lagos/NSIA-LUTH Cancer Centre, Lagos, Nigeria.ORCID https://orcid.org/0000-0003-1599-9438
Nusirat AdedeweDepartment of Radiation Biology, Division of Radiotherapy and Radiodiagnosis, College of Medicine, University of Lagos/NSIA-LUTH Cancer Centre, Lagos, Nigeria.ORCID https://orcid.org/0000-0002-8677-8192
Adedayo JosephDepartment of Radiotherapy, Nigeria Sovereign Investment Authority-Lagos University Teaching Hospital, Lagos, Nigeria.ORCID https://orcid.org/0000-0002-7938-1218
Omolara FatiregunMedical Physics Unit, Federal Medical Centre Asaba, Asaba, Nigeria.ORCID https://orcid.org/0000-0001-9219-9069
Akintayo OmojolaDepartment of Radiology, Lagos State University College of Medicine, Lagos, Nigeria.ORCID https://orcid.org/0000-0002-8741-3881
Abe AdebayoDepartment of Radiotherapy, Lagos University Teaching Hospital, Lagos, Nigeria.ORCID https://orcid.org/0000-0003-1604-6815
Esther OluwadaraDepartment of Radiation Biology, Division of Radiotherapy and Radiodiagnosis, College of Medicine, University of Lagos/NSIA-LUTH Cancer Centre, Lagos, Nigeria.ORCID https://orcid.org/0000-0001-6001-949X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aimed to evaluate the dosimetric properties of treatment plans obtained from three-dimensional conformal radiotherapy (3D-CRT) and intensity-modulated radiotherapy techniques (IMRT) plans for left chest wall breast cancer patients. MATERIALS AND

methodsA total of 20 patients with left-sided chest wall radiotherapy were randomly selected with the dose prescriptions: 42 Gy and 45 Gy in 15 and 18 fractions, respectively. Treatment plans were obtained using 3D-CRT and IMRT for each patient. Five to seven beams were used for IMRT, while tangential beams were used for 3D-CRT. Planning target volume, D

resultsIMRT showed a significant improvement in HI compared to 3D-CRT (p<0.0001). Although there was no significant difference in sparing of the left lung between both plans for high-dose volumes (V20: 18.2 vs 30.55, p<0.0001), (V25: 11.17 vs 28.12, p<0.0001). IMRT however showed supremacy to 3D-CRT with high-dose volumes for the heart, including V20 (4.44 vs 10.29, p = 0.02), V25 (2.08 vs 8.94, p = 0.002). 3D-CRT was better than IMRT in low-dose volumes for left lung (V5: 92.23 vs 56.60, p<0.001; V10: 60.98 vs 47.20, p = 0.04) and heart (V5: 57.45 vs 30.39, p = 0.004).

conclusionIMRT showed better homogeneity and sparing of high-dose volumes to OAR than 3D-CRT. On the other hand, 3D-CRT showed a reduction of low-dose volumes to OARs than IMRT.

Indexed as

3D-CRTIMRTorgans at riskPMRTradiotherapy

Identifiers

PMID34263152
PMCPMC8246049

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.