Evidence map›Paper›PMID 34263070›Full record

ArticleJGH open : an open access journal of gastroenterology and hepatology2021

Clinical characteristics of sarcopenia in patients with alcoholic liver cirrhosis.

Chisato Saeki, Tomoya Kanai, Masanori Nakano, Tsunekazu Oikawa, Yuichi Torisu, Masayuki Saruta, Akihito Tsubota

Open access · goldAbstract read
In one paragraph

Article in JGH open : an open access journal of gastroenterology and hepatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Body Composition in Chronic Liver Disease.International journal of molecular sciences · 2024
    Review
  2. Article
  3. Article
  4. Insulin-like growth factor 1 and dehydroepiandrosterone levels in alcoholic liver cirrhosis.JGH open : an open access journal of gastroenterology and hepatology · 2022
    Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Chisato SaekiDivision of Gastroenterology and Hepatology, Department of Internal Medicine The Jikei University School of Medicine Tokyo Japan.ORCID https://orcid.org/0000-0002-7407-6142
Tomoya KanaiDivision of Gastroenterology and Hepatology, Department of Internal Medicine The Jikei University School of Medicine Tokyo Japan.
Masanori NakanoDivision of Gastroenterology and Hepatology, Department of Internal Medicine The Jikei University School of Medicine Tokyo Japan.
Tsunekazu OikawaDivision of Gastroenterology and Hepatology, Department of Internal Medicine The Jikei University School of Medicine Tokyo Japan.ORCID https://orcid.org/0000-0003-1365-5391
Yuichi TorisuDivision of Gastroenterology and Hepatology, Department of Internal Medicine The Jikei University School of Medicine Tokyo Japan.
Masayuki SarutaDivision of Gastroenterology and Hepatology, Department of Internal Medicine The Jikei University School of Medicine Tokyo Japan.
Akihito TsubotaCore Research Facilities, Research Center for Medical Science The Jikei University School of Medicine Tokyo Japan.
Jikei University School of Medicine · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimSarcopenia frequently develops in patient with liver cirrhosis (LC). Ethanol reduces muscle protein synthesis and accelerates proteolysis. However, the relationship between heavy alcohol consumption and sarcopenia remains controversial. This study aimed to investigate the characteristics and prevalence of sarcopenia among patients with alcoholic LC (ALC) in real-world clinical settings.

methodsThis cross-sectional study included 181 patients with LC. Heavy alcohol consumption was defined as >60 g/day. Sarcopenia was diagnosed according to the Japan Society of Hepatology criteria.

resultsAmong the 181 patients, 64 (35.4%) were diagnosed with ALC. Patients with ALC were younger (median, 61.5

conclusionPatients with ALC were younger and had a lower prevalence of sarcopenia, despite advanced disease stage/impaired liver function reserve, compared to those with non-ALC in real-world clinical settings. However, older age was strongly associated with sarcopenia, even in patients with ALC. There was no significant influence of heavy alcohol consumption on the development of sarcopenia.

Indexed as

alcohol consumptionalcoholic liver cirrhosissarcopenia

Identifiers

PMID34263070
PMCPMC8264247
OpenAlexW3171797592

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.