Evidence map›Paper›PMID 34263017›Full record

ArticleCurrent opinion in behavioral sciences2021

Precision Estimates of Parallel Distributed Association Networks: Evidence for Domain Specialization and Implications for Evolution and Development.

Lauren M DiNicola, Randy L Buckner

Open access · hybridAbstract read
In one paragraph

Article in Current opinion in behavioral sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 1 pooled it
5.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 1 synthesis or guideline pooled it, 60 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. The molecular and cellular underpinnings of human brain lateralization.bioRxiv : the preprint server for biology · 2025
    Article
  10. Parallel systems for social and spatial cognition reaching the cortical apex.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  11. Article
  12. Default Mode Network Functional Connectivity As a Transdiagnostic Biomarker of Cognitive Function.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2025
    Review
  13. Article
  14. Article
  15. Article
  16. Expansion of a conserved architecture drives the evolution of the primate visual cortex.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  17. Article
  18. Article
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Lauren M DiNicolaDepartment of Psychology, Center for Brain Science, Harvard University, Cambridge, MA 02138 USA.
Randy L BucknerDepartment of Psychology, Center for Brain Science, Harvard University, Cambridge, MA 02138 USA.
Athinoula A. Martinos Center for Biomedical Imaging · USHarvard University · US

Funding

The neural network of OCD, linking NHP and human studiesP50MH106435 · NIMH · UNIVERSITY OF ROCHESTER · PI Suzanne N Haber · 2015 to 2026
$28.9M
Upgrade Siemens MAGNETOM Trio to MAGNETOM Prisma Fit 3T Human MRI SystemS10OD020039 · OD · HARVARD UNIVERSITY · PI BUCKNER, RANDY L · 2015 to 2015
$600k
NIH HHS S10 OD020039NIMH NIH HHS P50 MH106435
6 · The paper itself

Abstract

Humans can reason about other minds, comprehend language and imagine. These abilities depend on association regions that exhibit evolutionary expansion and prolonged postnatal development. Precision maps within individuals reveal these expanded zones are populated by multiple specialized networks that each possess a spatially distributed motif but remain anatomically separated throughout the cortex for language, social and mnemonic / spatial functions. Rather than converge on multi-domain regions or hubs, these networks include distinct regions within rostral prefrontal and temporal association zones. To account for these observations, we propose the expansion-fractionation-specialization (EFS) hypothesis: evolutionary expansion of human association cortex may have allowed for an archetype distributed network to fractionate into multiple specialized networks. Human development may recapitulate fractionation and specialization when these abilities emerge.

Indexed as

association cortexlanguageprecision neuroimagingrememberingtheory of mind

Identifiers

PMID34263017
PMCPMC8274557
OpenAlexW3159317088

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.