Evidence map›Paper›PMID 34262881›Full record

ArticleFrontiers in cellular and infection microbiology2021

Congenital Asplenia Interrupts Immune Homeostasis and Leads to Excessive Systemic Inflammation in Zebrafish.

Lang Xie, Zheyu Chen, Hui Guo, Yixi Tao, Xiaomin Miao, Ronghua Wu, Yun Li

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Lang XieInstitute of Three Gorges Ecological Fisheries of Chongqing, College of Fisheries, Southwest University, Chongqing, China.
Zheyu ChenInstitute of Three Gorges Ecological Fisheries of Chongqing, College of Fisheries, Southwest University, Chongqing, China.
Hui GuoInstitute of Three Gorges Ecological Fisheries of Chongqing, College of Fisheries, Southwest University, Chongqing, China.
Yixi TaoInstitute of Three Gorges Ecological Fisheries of Chongqing, College of Fisheries, Southwest University, Chongqing, China.
Xiaomin MiaoInstitute of Three Gorges Ecological Fisheries of Chongqing, College of Fisheries, Southwest University, Chongqing, China.
Ronghua WuInstitute of Three Gorges Ecological Fisheries of Chongqing, College of Fisheries, Southwest University, Chongqing, China.
Yun LiInstitute of Three Gorges Ecological Fisheries of Chongqing, College of Fisheries, Southwest University, Chongqing, China.
Southwest University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Splenectomy or congenital asplenia in humans increases susceptibility to infections. We have previously reported that congenital asplenia in zebrafish reduces resistance to

Indexed as

SplenectomyZebrafishAnimalsHomeostasisHumansInflammationSpleencongenital aspleniaexcessive inflammationsplenic anti-inflammatory reflexsystemic immunitytranscriptome

Identifiers

PMID34262881
PMCPMC8274418
OpenAlexW3176525110

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.