ArticleFrontiers in oncology2021
The Proton-Boron Reaction Increases the Radiobiological Effectiveness of Clinical Low- and High-Energy Proton Beams: Novel Experimental Evidence and Perspectives.
Article in Frontiers in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 54 citations in OpenAlex.
- Evaluation of a Boron-Conjugated SRC Inhibitor Combined with Proton and X-Ray Irradiation in U-87 MG and U-87 MG IDH1Pharmaceuticals (Basel, Switzerland) · 2026Article
- Light Quality Modulates the Antioxidant Properties of "Microtom" Fruits: A Pilot Study Testing the Radioprotective Effect on Human Cells.International journal of molecular sciences · 2026Article
- Sensitization for proton beam therapy usingScientific reports · 2025Article
- Assessment of Carrier-Free Metallacarboranes for Targeted Radiation Therapies PBFT and BNCT: Comparative Cellular Effects and Dosimetry Studies with [Pharmaceuticals (Basel, Switzerland) · 2025Article
- Variations among glioblastoma cell lines in boron-mediated enhancement of cell killing by proton beams.Scientific reports · 2025Article
- Unravelling physical and radiobiological effects of proton boron fusion reaction with anionic metallacarboranes ([o-COSAN]EJNMMI research · 2025Article
- Proton boron capture therapy: microdosimetry and treatment planning study with boron.Frontiers in oncology · 2025Article
- Proton-boron capture interaction enhances killing of radiation resistant cancer cells.Frontiers in oncology · 2025Article
- Microdosimetric Simulation of Gold-Nanoparticle-Enhanced Radiotherapy.International journal of molecular sciences · 2024Article
- First independent validation of the proton-boron capture therapy concept.Scientific reports · 2024Article
- Study of Nuclear Reactions in Therapy of Tumors with Proton Beams.International journal of molecular sciences · 2023Article
- Boron Nanoparticle-Enhanced Proton Therapy for Cancer Treatment.Nanomaterials (Basel, Switzerland) · 2023Article
- Current State and Prospectives for Proton Boron Capture Therapy.Biomedicines · 2023Review
- Proton boron capture therapy (PBCT) induces cell death and mitophagy in a heterotopic glioblastoma model.Communications biology · 2023Article
- Experimental validation of proton boron capture therapy for glioma cells.Scientific reports · 2023Article
- UsingScientific reports · 2022Article
- Differential Radiomodulating Action ofAntioxidants (Basel, Switzerland) · 2022Article
Corrections and comments
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Authors and funding
22 authors at 12 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Protontherapy is a rapidly expanding radiotherapy modality where accelerated proton beams are used to precisely deliver the dose to the tumor target but is generally considered ineffective against radioresistant tumors. Proton-Boron Capture Therapy (PBCT) is a novel approach aimed at enhancing proton biological effectiveness. PBCT exploits a nuclear fusion reaction between low-energy protons and
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Registered trials
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