Evidence map›Paper›PMID 34262773›Full record

ArticleSAGE open medical case reports2021

Intravenous immunoglobulin as adjuvant therapy for COVID-19: A case report and literature review.

Carlos A Flores-Oria, Emilio Saturno, Supriya Ramanathan, Diana J Martinez Castillo, Roshni Kumar, Nelson Ferrer, Afnan Mossaad, Maria E Tellez, Cindy Jon, Sara C Waters and 1 more

Open access · goldAbstract read
In one paragraph

Article in SAGE open medical case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Carlos A Flores-OriaDivision of Pulmonology, Department of Pediatrics, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, USA.ORCID https://orcid.org/0000-0002-9337-6175
Emilio SaturnoWest Jefferson Medical Center, Marrero, LA, USA.
Supriya RamanathanDepartment of Pediatrics, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, USA.
Diana J Martinez CastilloDepartment of Pediatrics, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, USA.
Roshni KumarBellaire High School, Bellaire, TX, USA.
Nelson FerrerHospital Pacifica Salud, Panama.
Afnan MossaadDepartment of Internal Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, USA.
Maria E TellezSchool of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA.
Cindy JonDivision of Pulmonology, Department of Pediatrics, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, USA.
Sara C WatersDepartment of Internal Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, USA.
Ricardo A MosqueraDivision of Pulmonology, Department of Pediatrics, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, USA.
The University of Texas Health Science Center at Houston · USHospital Punta Pacifica · PAWest Jefferson Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Severe acute respiratory syndrome coronavirus 2 has infected and caused the death of an alarming number of individuals worldwide. No specific treatment has been internationally standardized for coronavirus disease 2019 (COVID-19); however, in some cases, intravenous immunoglobulin (IVIG) has been used as adjuvant treatment in critically ill patients with COVID-19 pneumonia. We report a case of a 50-year-old man with severe COVID-19 pneumonia who received 5 days course of IVIG as adjuvant therapy. Invasive respiratory support was avoided. The patient had a successful recovery and was discharged without supplemental oxygen. A high dose of IVIG may improve survival in patients with severe COVID-19 pneumonia. In the current report, we reviewed literature on how IVIG use may improve the early stages of the disease.

Indexed as

Coronavirus disease 2019hypoxemiaintravenous immunoglobulinIVIGsevere acute respiratory syndrome coronavirus 2

Identifiers

PMID34262773
PMCPMC8252403
OpenAlexW3177312531

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.