ArticleSAGE open medicine2021
COVID-19 and dysnatremia: A comparison between COVID-19 and non-COVID-19 respiratory illness.
Article in SAGE open medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.
- Association of hypernatremia with mortality in patients with COVID-19: A systematic review and meta-analysis.Immunity, inflammation and disease · 2023Pooled it
- Dysnatremia and Endocrine Alterations in Hospitalized COVID-19 Patients: Markers of Systemic Stress Rather than Independent Predictors of Outcomes.Biomedicines · 2026Article
- Osmolality as a strong predictor of COVID-19 mortality and its possible links to other biomarkers.PloS one · 2025Article
- Implications of Dysnatremia and Endocrine Disturbances in COVID-19 Patients.International journal of molecular sciences · 2024Review
- Observational
- [Pituitary and COVID-19: review].Problemy endokrinologii · 2022Review
- Prevalence, prognostic value, pathophysiology, and management of hyponatraemia in children and adolescents with COVID-19.Acta bio-medica : Atenei Parmensis · 2021Review
- Prevalence and outcomes of hyponatremia among COVID-19 patients: A systematic review and meta-analysis.International journal of health sciencesReview
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo investigate the occurrence of disorders of water and sodium balance in COVID-19 in our clinic.
methodsIn this retrospective chart review, patients were included if a polymerase chain test result for SARS-CoV-2 was obtained and if at least one plasma sodium concentration measurement was obtained during the period from March to June 2020. The occurrences of hyponatremia and hypernatremia were compared between 193 SARS-CoV-2-positive and 138 SARS-CoV-2-negative patients. A χ² test was used to determine statistical significance, and the corresponding
resultsHypernatremia was significantly more frequently observed in COVID-19 patients, in 38% (74 of 193), versus only 8% in SARS-CoV-2-negative patients (11 of 138) (
conclusionDisorders of water and sodium balance-and especially hypernatremia-seem to be a common occurrence in COVID-19 patients. This has important implications for the treatment of COVID-19 patients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.