Evidence map›Paper›PMID 34262731›Full record

ArticleFood science & nutrition2021

Cerebroprotein hydrolysate-I protects senescence-induced by D-galactose in PC12 cells and mice.

Lin Zhu, Yingjuan Liu, Xiaolin Wu, Yuqian Ren, Qinghua Zhang, Leiming Ren, Yunliang Guo

Open access · hybridAbstract read
In one paragraph

Article in Food science & nutrition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Lin ZhuInstitute of Cerebrovascular Diseases Taishan Scholars Construction Project Excellent Innovative Team of Shandong Province Medical Research Center The Affiliated Hospital of Qingdao University Qingdao China.
Yingjuan LiuInstitute of Cerebrovascular Diseases Taishan Scholars Construction Project Excellent Innovative Team of Shandong Province Medical Research Center The Affiliated Hospital of Qingdao University Qingdao China.
Xiaolin WuInstitute of Cerebrovascular Diseases Taishan Scholars Construction Project Excellent Innovative Team of Shandong Province Medical Research Center The Affiliated Hospital of Qingdao University Qingdao China.
Yuqian RenInstitute of Cerebrovascular Diseases Taishan Scholars Construction Project Excellent Innovative Team of Shandong Province Medical Research Center The Affiliated Hospital of Qingdao University Qingdao China.
Qinghua ZhangDepartment of Neurology Shandong Second Provincial General Hospital Jinan China.
Leiming RenInstitute of Chinese Integrative Medicine Hebei Medical University Shijiazhuang China.
Yunliang GuoInstitute of Cerebrovascular Diseases Taishan Scholars Construction Project Excellent Innovative Team of Shandong Province Medical Research Center The Affiliated Hospital of Qingdao University Qingdao China.ORCID https://orcid.org/0000-0003-3107-8073
Qingdao University · CNHebei Medical University · CNSecond Hospital of Shandong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cerebroprotein hydrolysate-I (CH-I),a mixture of peptides extracted from porcine brain tissue,has shown a neuroprotective effect, but its role in brain senescence is unclear. In the present study, we established a senescence model of PC12 cells and mice to investigate the effect of CH-I on brain senescence via JAK2/STAT3 pathway. The results showed that CH-I could improve cell viability, inhibit the apoptosis of cells, and reduce the senescence-positive cells induced by D-galactose. In

Indexed as

cerebroprotein hydrolysate‐ID‐galactosemicePC12 cellssenescencetelomerase

Identifiers

PMID34262731
PMCPMC8269606
OpenAlexW3161997664

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.