Evidence map›Paper›PMID 34262711›Full record

ArticleFood science & nutrition2021

The effect of food ration bar enriched with β-alanine, L-arginine, and Nigella sativa on performance and inflammation following intense military training: A double-blind randomized clinical trial.

Saeid Hadi, Mahsa Miryan, Davood Soleimani, Reza Amani, Mostafa Mazaheri Tehrani, Vahid Hadi, Morad Esmaiil Zali, Negin Mosalmanzadeh, Gholamreza Askari

Open access · hybridAbstract read
In one paragraph

Article in Food science & nutrition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 1 country.

Saeid HadiDepartment of Community Nutrition School of Nutrition and Food Sciences Isfahan University of Medical Sciences Isfahan Iran.ORCID https://orcid.org/0000-0002-7648-2259
Mahsa MiryanNutrition Research Center Student Research Committee Department of Clinical Nutrition School of Nutrition and Food Sciences Tabriz University of Medical Sciences Tabriz Iran.ORCID https://orcid.org/0000-0002-1051-6911
Davood SoleimaniNutritional Sciences Department School of Nutrition Sciences and Food Technology Kermanshah University of Medical Sciences Kermanshah Iran.ORCID https://orcid.org/0000-0002-9017-3743
Reza AmaniDepartment of Community Nutrition School of Nutrition and Food Sciences Isfahan University of Medical Sciences Isfahan Iran.ORCID https://orcid.org/0000-0002-0074-4080
Mostafa Mazaheri TehraniDepartment of Food Science and Technology Faculty of Agriculture Ferdowsi University of Mashhad Mashhad Iran.ORCID https://orcid.org/0000-0002-4730-4947
Vahid HadiDepartment of Health, Science and Research Branch AJA University of Medical Sciences Tehran Iran.ORCID https://orcid.org/0000-0002-6458-950X
Morad Esmaiil ZaliDepartment of Management and Health Economy Faculty of Medicine AJA University of medical sciences Tehran Iran.
Negin MosalmanzadehDepartment of Nutrition Sciences Varastegan Institute for Medical Sciences Mashhad Iran.
Gholamreza AskariDepartment of Community Nutrition School of Nutrition and Food Sciences Isfahan University of Medical Sciences Isfahan Iran.ORCID https://orcid.org/0000-0003-1194-9687
Isfahan University of Medical Sciences · IRAja University of Medical Sciences · IRFerdowsi University of Mashhad · IRKermanshah University of Medical Sciences · IRMashhad University of Medical Sciences · IRTabriz University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere are growing interests in using dietary supplements to improve athletic performance. This study aimed to evaluate the effect of the food ration bar enriched with β-alanine, L-arginine, and Nigella sativa on athletic performance and inflammation following intense military training.

methodsThis double-blind, randomized, controlled clinical trial was conducted on 54 new cadets. Eligible participants were randomly assigned in a 1:1 ratio to receive food ration bars enriched with arginine (2 g/day), β-alanine (2 g/day), and Nigella sativa (2 g/day) or nonenriched food ration bars during a 2-week military training. Aerobic and anaerobic performances were evaluated by the Cooper and RAST tests, respectively.

resultsA significant increase in anaerobic powers (min, mean, and max) and a significant reduction in fatigue index were observed in the intervention group as compared to the control group, even after the adjustment for confounding factors. Also, increased levels of hs-CRP and TNF-α following military training were significantly lower in the intervention group as compared to the control group (hs-CRP: 0.55 ± 0.1 versus 2.43 ± 0.1 mg/L;

conclusionsOur results showed that the combination of β-alanine, L-arginine, and Nigella sativa can improve anaerobic performance and reduce inflammation following intense physical activities. Further studies with long-term duration are needed to confirm the cumulative/synergic effects of these ingredients in trained and nontrained subjects.

Indexed as

inflammationL‐argininemilitary trainingNigella sativaVO2 maxβ‐alanine

Identifiers

PMID34262711
PMCPMC8269545
OpenAlexW3163332989

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.