Evidence map›Paper›PMID 34262629›Full record

ArticleChemCatChem2021

A Structural View on the Stereospecificity of Plant Borneol-Type Dehydrogenases.

Andrea M Chánique, Nicole Dimos, Ivana Drienovská, Elia Calderini, Mónica P Pantín, Carl P O Helmer, Michael Hofer, Volker Sieber, Loreto P Parra, Bernhard Loll and 1 more

Open access · hybridAbstract read
In one paragraph

Article in ChemCatChem, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. CryoEM analysis of small plant biocatalysts at sub-2 Å resolution.Acta crystallographica. Section D, Structural biology · 2022
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 3 countries.

Andrea M ChániqueInstitute of Molecular Biotechnology Graz University of Technology Petersgasse 14 8010 Graz Austria.ORCID 0000-0003-0642-1351
Nicole DimosInstitute of Chemistry and Biochemistry Department of Biology Chemistry Pharmacy Laboratory of Structural Biochemistry Free University of Berlin Takustr. 6 14195 Berlin Germany.ORCID 0000-0001-5398-7310
Ivana DrienovskáInstitute of Molecular Biotechnology Graz University of Technology Petersgasse 14 8010 Graz Austria.ORCID 0000-0003-1715-4236
Elia CalderiniInstitute of Molecular Biotechnology Graz University of Technology Petersgasse 14 8010 Graz Austria.ORCID 0000-0003-3991-6182
Mónica P PantínInstitute of Molecular Biotechnology Graz University of Technology Petersgasse 14 8010 Graz Austria.
Carl P O HelmerInstitute of Chemistry and Biochemistry Department of Biology Chemistry Pharmacy Laboratory of Structural Biochemistry Free University of Berlin Takustr. 6 14195 Berlin Germany.ORCID 0000-0001-7195-9938
Michael HoferFraunhofer Institute for Interfacial Engineering and Biotechnology IGB Schulgasse 11a 94315 Straubing Germany.
Volker SieberFraunhofer Institute for Interfacial Engineering and Biotechnology IGB Schulgasse 11a 94315 Straubing Germany.
Loreto P ParraInstitute for Biological and Medical Engineering Schools of Engineering Medicine and Biological Sciences Pontificia Universidad Católica de Chile Vicuña Mackenna 4860 7810000 Santiago Chile.
Bernhard LollInstitute of Chemistry and Biochemistry Department of Biology Chemistry Pharmacy Laboratory of Structural Biochemistry Free University of Berlin Takustr. 6 14195 Berlin Germany.ORCID 0000-0001-7928-4488
Robert KouristInstitute of Molecular Biotechnology Graz University of Technology Petersgasse 14 8010 Graz Austria.ORCID 0000-0002-2853-3525
Institute of Molecular Biotechnology · ATFreie Universität Berlin · DEFraunhofer Institute for Interfacial Engineering and Biotechnology · DEPontificia Universidad Católica de Chile · CL

Funding

Austrian Science Fund FWF P 31001
6 · The paper itself

Abstract

The development of sustainable processes for the valorization of byproducts and other waste streams remains an ongoing challenge in the field of catalysis. Racemic borneol, isoborneol and camphor are currently produced from α-pinene, a side product from the production of cellulose. The pure enantiomers of these monoterpenoids have numerous applications in cosmetics and act as reagents for asymmetric synthesis, making an enzymatic route for their separation into optically pure enantiomers a desirable goal. Known short-chain borneol-type dehydrogenases (BDHs) from plants and bacteria lack the required specificity, stability or activity for industrial utilization. Prompted by reports on the presence of pure (-)-borneol and (-)-camphor in essential oils from rosemary, we set out to investigate dehydrogenases from the genus

Indexed as

BorneolEnantioselectivitySalvia rosmarinusShort-chain dehydrogenase-reductase (SDR)Terpenoids

Identifiers

PMID34262629
PMCPMC8261865
OpenAlexW3130413735

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.