Evidence map›Paper›PMID 34262558›Full record

ArticleFrontiers in immunology2021

Functional miR-142a-3p Induces Apoptosis and Macrophage Polarization by Targeting

Lizhu Tao, Yifan Pang, Anqi Wang, Lisen Li, Yubang Shen, Xiaoyan Xu, Jiale Li

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
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  4. Potential Role of microRNAs in Response toArchives of Razi Institute · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Lizhu TaoKey Laboratory of Freshwater Aquatic Genetic Resources Ministry of Agriculture and Rural Affairs, Shanghai Ocean University, Shanghai, China.
Yifan PangNational Demonstration Center for Experimental Fisheries Science Education, Shanghai Ocean University, Shanghai, China.
Anqi WangShanghai Engineering Research Center of Aquaculture, Shanghai Ocean University, Shanghai, China.
Lisen LiComparative Endocrinology and Integrative Biology, Centre of Marine Sciences, Universidade Do Algarve, Faro, Portugal.
Yubang ShenNational Demonstration Center for Experimental Fisheries Science Education, Shanghai Ocean University, Shanghai, China.
Xiaoyan XuKey Laboratory of Freshwater Aquatic Genetic Resources Ministry of Agriculture and Rural Affairs, Shanghai Ocean University, Shanghai, China.
Jiale LiKey Laboratory of Freshwater Aquatic Genetic Resources Ministry of Agriculture and Rural Affairs, Shanghai Ocean University, Shanghai, China.
Shanghai Ocean University · CNMinistry of Agriculture and Rural Affairs · CNUniversity of Algarve · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the process of microbial invasion, the inflammation reaction is induced to eliminate the pathogen. However, un-controlled or un-resolved inflammation can lead to tissue damage and death of the host. MicroRNAs (miRNAs) are the signaling regulators that prevent the uncontrolled progress of an inflammatory response. Our previous work strongly indicated that miR-142a-3p is related to the immune regulation in grass carp. In the present study, we found that the expression of miR-142a-3p was down-regulated after infection by

Indexed as

Aeromonas hydrophilaAnimalsApoptosisCarpsCells, CulturedCytokinesGlucose Transporter Type 3Gram-Negative Bacterial InfectionsInflammationKidneyKupffer CellsMacrophage ActivationMacrophagesMicroRNAsSignal TransductionCytokinesGlucose Transporter Type 3MicroRNAsapoptosisgrass carpinflammationmacrophagemiR-142a-3p

Identifiers

PMID34262558
PMCPMC8273434
OpenAlexW3173883609

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.