Evidence map›Paper›PMID 34262416›Full record

ArticleFood & nutrition research2021

The metabolic effect of fructose on normal rats in a mild dose with glucose and saccharose as control.

Ge Song, Wentao Qi, Yong Wang, Shaojie Pang, Yong Li

Open access · goldAbstract read
In one paragraph

Article in Food & nutrition research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Ge SongInstitute of Grain Quality and Nutrition Research, Academy of National Food and Strategic Reserves Administration, Beijing, People's Republic of China.
Wentao QiInstitute of Grain Quality and Nutrition Research, Academy of National Food and Strategic Reserves Administration, Beijing, People's Republic of China.
Yong WangInstitute of Grain Quality and Nutrition Research, Academy of National Food and Strategic Reserves Administration, Beijing, People's Republic of China.
Shaojie PangInstitute of Grain Quality and Nutrition Research, Academy of National Food and Strategic Reserves Administration, Beijing, People's Republic of China.
Yong LiDepartment of Nutrition and Food Hygiene, School of Public Health, Peking University, Beijing, People's Republic of China.
Academy of State Administration of Grain · CNPeking University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsTo study the metabolic effects of fructose, glucose and saccharose in a moderate dose by analyzing changes of blood indicators, pancreas inflammation, liver fat accumulation and intestinal microbiota in normal Sprague-Dawley (SD) rats. SUBJECTS AND

methodsSix-week-old rats were assigned to four groups (

resultsNo significant differences in body weight and blood parameters including total cholesterol (TC), total triglyceride (TG), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), lipase (LPS) and free fatty acid (FFA) among the Con, Glu, Sac and the Fru group. The fructose can significantly (

conclusionFructose, glucose and sucrose made no significant changes on rats in body weight, blood indicators, organ index and bacterial diversity. Moreover, fructose can potentially attenuate fasting and postprandial blood-glucose increase, pancreas inflammation and liver-fat accumulation when compared to glucose in mild doses. The relative abundance of six kinds of bacterial genera was found significantly different between rats fed on fructose and glucose.

Indexed as

fructoseglucoseintestinal micro biotametabolic effectmild dosesaccharose

Identifiers

PMID34262416
PMCPMC8254463
OpenAlexW3160680644

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.