Evidence map›Paper›PMID 34262397›Full record

ArticleReproductive medicine and biology2021

Relationship between follicular size and developmental capacity of oocytes under controlled ovarian hyperstimulation in assisted reproductive technologies.

Isao Tamura, Mai Kawamoto-Jozaki, Taishi Fujimura, Yumiko Doi-Tanaka, Haruka Takagi, Yuichiro Shirafuta, Yumiko Mihara, Toshiaki Taketani, Hiroshi Tamura, Norihiro Sugino

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Article in Reproductive medicine and biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Isao TamuraDepartment of Obstetrics and Gynecology Yamaguchi University Graduate School of Medicine Ube Japan.ORCID https://orcid.org/0000-0002-0737-5556
Mai Kawamoto-JozakiDepartment of Obstetrics and Gynecology Yamaguchi University Graduate School of Medicine Ube Japan.
Taishi FujimuraDepartment of Obstetrics and Gynecology Yamaguchi University Graduate School of Medicine Ube Japan.
Yumiko Doi-TanakaDepartment of Obstetrics and Gynecology Yamaguchi University Graduate School of Medicine Ube Japan.
Haruka TakagiDepartment of Obstetrics and Gynecology Yamaguchi University Graduate School of Medicine Ube Japan.
Yuichiro ShirafutaDepartment of Obstetrics and Gynecology Yamaguchi University Graduate School of Medicine Ube Japan.
Yumiko MiharaDepartment of Obstetrics and Gynecology Yamaguchi University Graduate School of Medicine Ube Japan.
Toshiaki TaketaniDepartment of Obstetrics and Gynecology Yamaguchi University Graduate School of Medicine Ube Japan.
Hiroshi TamuraDepartment of Obstetrics and Gynecology Yamaguchi University Graduate School of Medicine Ube Japan.ORCID https://orcid.org/0000-0001-6258-4572
Norihiro SuginoDepartment of Obstetrics and Gynecology Yamaguchi University Graduate School of Medicine Ube Japan.ORCID https://orcid.org/0000-0001-8874-7931

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe investigate the relationships between oocyte developmental capacity and follicular size of its origin in Japanese women: those undergoing conventional IVF (cIVF) and ICSI, respectively.

methodsA total of 3377 follicles were punctured separately and were classified into three groups (large, medium, and small) by their diameters. A total of 1482 retrieved oocytes were individually cultured and received cIVF or ICSI. The oocytes receiving ICSI were denuded and the number of mature (MII) oocytes was counted.

resultsThe oocyte retrieval rates and the proportion of MII oocytes were significantly lower in small follicles than in large follicles. Under cIVF, the fertilization rate was significantly lower in oocytes from small follicles than large follicles. Under ICSI, the fertilization rate for MII oocytes was not significantly related to follicular size. Follicular size was not significantly related to the development potential to blastocyst and pregnancy rate for either the cIVF oocytes or the ICSI oocytes.

conclusionsAlthough the fertilization rate by cIVF is low in oocytes from small follicles due to the lower proportion of mature oocytes, their development potential is comparable to that of oocytes from larger follicles if they could be fertilized. Under ICSI using mature oocytes, their development potential is not related to follicular size.

Indexed as

blastocystfollicular sizeICSIIVFoocyte development

Identifiers

PMID34262397
PMCPMC8254166

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.