ArticleCommunications biology2021
Dorsal and ventral striatal functional connectivity shifts play a potential role in internet gaming disorder.
Article in Communications biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 3 of them syntheses that pooled it.
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Who cites it
32 citing papers in PubMed, 3 syntheses or guidelines pooled it, 72 citations in OpenAlex.
- Common and disorder-specific aberrant activation during reward and loss processing in major depressive disorder and addiction: a meta-analysis of fMRI studies.Molecular psychiatry · 2026Pooled it
- Neural mechanisms of behavioral addiction: An ALE meta-analysis and MACM analysis.Journal of behavioral addictions · 2025Pooled it
- The resting-state brain activity signatures for addictive disorders.Med (New York, N.Y.) · 2024Pooled it
- Incentive valence differentially engages open- and closed-loop basal ganglia circuits during movement initiation.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Internet addiction is associated with differences in static and dynamic hippocampal functional connectivity in young adults: the mediating role of emotion regulation difficulties.Frontiers in psychiatry · 2026Article
- Reciprocal brain-behavior associations in gambling disorder revealed by theta cordance and directional predictive modeling.Frontiers in behavioral neuroscience · 2026Article
- Abnormal ventromedial-to-dorsolateral hierarchical topography of striatal circuits in cocaine use disorder and its modulations by brain stimulation.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2025Article
- Individual-specific subspace of altered functional connectivity predicts clinical symptoms in Internet gaming disorder.Journal of behavioral addictions · 2025Article
- Increasingly dependent on habit? A study on the electrophysiological mechanisms of goal-directed and habitual control in internet gaming disorder.Journal of behavioral addictions · 2025Article
- Altered dynamic reconfiguration of brain functional networks during gaming and deprivation in individuals with internet gaming disorder.Journal of behavioral addictions · 2025Article
- Transformative Effects of Mindfulness Meditation Training on the Dynamic Reconfiguration of Executive and Default Mode Networks in Internet Gaming Disorder.Biological psychiatry global open science · 2025Article
- Gaming disorder: Neural mechanisms and ongoing debates.Journal of behavioral addictions · 2025Review
- Screen use in children - two sides of the coin: a critical narrative review.Dementia & neuropsychologia · 2025Review
- Disrupted Cross-Scale Network Associated With Cognitive-Emotional Disorders in Sudden Sensorineural Hearing Loss.CNS neuroscience & therapeutics · 2025Article
- Decoding and modifying dynamic attentional bias in gaming disorder.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024Article
- Biomarkers of Internet Gaming Disorder-A Narrative Review.Journal of clinical medicine · 2024Review
- Wanting-liking dissociation and altered dopaminergic functioning: Similarities between internet gaming disorder and tobacco use disorder.Journal of behavioral addictions · 2024Article
- From compulsivity to compulsion: the neural basis of compulsive disorders.Nature reviews. Neuroscience · 2024Review
- Ten years of research on the treatments of internet gaming disorder: A scoping review and directions for future research.Journal of behavioral addictions · 2024Article
- Bimodal Transformer with Regional EEG Data for Accurate Gameplay Regularity Classification.Brain sciences · 2024Article
Corrections and comments
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Authors and funding
7 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Animal models suggest transitions from non-addictive to addictive behavioral engagement are associated with ventral-to-dorsal striatal shifts. However, few studies have examined such features in humans, especially in internet gaming disorder (IGD), a proposed behavioral addiction. We recruited 418 subjects (174 with IGD; 244 with recreational game use (RGU)). Resting-state fMRI data were collected and functional connectivity analyses were performed based on ventral and dorsal striatal seeds. Correlations and follow-up spectrum dynamic causal model (spDCM) analyses were performed to examine relationships between the ventral/dorsal striatum and middle frontal gyrus (MFG). Longitudinal data were also analysed to investigate changes over time. IGD relative to RGU subjects showed lower ventral-striatum-to-MFG (mostly involving supplementary motor area (SMA)) and higher dorsal-striatum-to-MFG functional connectivity. spDCM revealed that left dorsal-striatum-to-MFG connectivity was correlated with IGD severity. Longitudinal data within IGD and RGU groups found greater dorsal striatal connectivity with the MFG in IGD versus RGU subjects. These findings suggest similar ventral-to-dorsal striatal shifts may operate in IGD and traditional addictions.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.