Evidence map›Paper›PMID 34261900›Full record

ReviewCardiology in review

Review of the Metabolic Risk Factors for Increased Severity of Coronavirus Disease-2019.

Tzvi Fishkin, Michael D Goldberg, William H Frishman

Open access · greenAbstract readReview
In one paragraph

Review in Cardiology in review. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Tzvi FishkinFrom the Department of Medicine, Westchester Medical Center, Valhalla, NY.
Michael D GoldbergDepartment of Medicine, Division of Endocrinology, New York Medical College/Westchester Medical Center, Valhalla, NY.
William H FrishmanDepartments of Medicine and Cardiology, New York Medical College/Westchester Medical Center, Valhalla, NY.
Westchester Medical Center · USNew York Medical College · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The coronavirus 2019 (COVID-19) pandemic has presented many new challenges to the healthcare community with the sheer number of individuals affected and the range of symptoms at presentation. Early findings have shown that increased age is an independent risk factor for COVID-19 severity. Diabetes and hypertension were also found to be strong independent risk factors for severe COVID-19. It was later discovered that obesity is a strong risk factor for severe disease as well. Possible mechanisms for the increased risk associated with metabolic disease include the increased prevalence of acute respiratory syndrome, immune cell dysfunction, and chronic inflammatory states associated with obesity and diabetes. Acknowledging these risk factors has consequences for addressing vaccination strategies as well as healthcare disparities.

Indexed as

ComorbidityCOVID-19Diabetes MellitusHumansHypertensionInflammationObesityRespiratory Distress SyndromeRisk FactorsSARS-CoV-2Severity of Illness Index

Identifiers

PMID34261900
PMCPMC8489576
OpenAlexW3181902387

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.