Evidence map›Paper›PMID 34261849›Full record

ArticleJournal of microbiology and biotechnology2021

Application of Engineered Zinc Finger Proteins Immobilized on Paramagnetic Beads for Multiplexed Detection of Pathogenic DNA.

Jiyoung Shim, Langley Williams, Dohyun Kim, Kisung Ko, Moon-Soo Kim

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of microbiology and biotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 56% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Advances in methods for rapid detection of Staphylococcus aureus and methicillin-resistant S. aureus.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Jiyoung ShimDepartment of Chemistry, Western Kentucky University, Bowling Green, KY 42101, USA.
Langley WilliamsDepartment of Chemistry, Western Kentucky University, Bowling Green, KY 42101, USA.
Dohyun KimDepartment of Mechanical Engineering, Myongji University, Yongin 17058, Republic of Korea.
Kisung KoDepartment of Medicine, College of Medicine, Chung-Ang University, Seoul 06974, Republic of Korea.
Moon-Soo KimDepartment of Chemistry, Western Kentucky University, Bowling Green, KY 42101, USA.
Western Kentucky University · USChung-Ang University · KRMyongji University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Micro-scale magnetic beads are widely used for isolation of proteins, DNA, and cells, leading to the development of in vitro diagnostics. Efficient isolation of target biomolecules is one of the keys to developing a simple and rapid point-of-care diagnostic. A zinc finger protein (ZFP) is a double-stranded (ds) DNA-binding domain, providing a useful scaffold for direct reading of the sequence information. Here, we utilized two engineered ZFPs (Stx2-268 and SEB-435) to detect the Shiga toxin (

Indexed as

Zinc FingersDNA, BacterialEnterotoxinsEscherichia coli O157Ferrosoferric OxideImmobilized ProteinsLimit of DetectionMicrobiological TechniquesShiga Toxin 2Staphylococcus aureusDNA, Bacterialenterotoxin B, staphylococcalEnterotoxinsFerrosoferric OxideImmobilized ProteinsShiga Toxin 2foodborne pathogenmagnetic beadsMultiplexed double-stranded DNA detectionzinc finger proteins

Identifiers

PMID34261849
PMCPMC9705829
OpenAlexW3181058395

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.