Evidence map›Paper›PMID 34261745›Full record

ReviewEuropean respiratory review : an official journal of the European Respiratory Society2021

Cough symptom severity in patients with refractory or unexplained chronic cough: a systematic survey and conceptual framework.

Elena Kum, Gordon H Guyatt, Tahira Devji, Yuting Wang, Layla Bakaa, Lucy Lan, Eva Liu, Alexander Mastrolonardo, Rachel Couban, Paul M O'Byrne and 1 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in European respiratory review : an official journal of the European Respiratory Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Elena KumDept of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, ON, Canada.
Gordon H GuyattDept of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, ON, Canada.
Tahira DevjiDept of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, ON, Canada.
Yuting WangDept of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, ON, Canada.
Layla BakaaDept of Psychology, Neuroscience, and Behaviour, McMaster University, Hamilton, ON, Canada.
Lucy LanMichael G. DeGroote School of Medicine, McMaster University, Hamilton, ON, Canada.ORCID https://orcid.org/0000-0003-4474-6018
Eva LiuMichael G. DeGroote School of Medicine, McMaster University, Hamilton, ON, Canada.
Alexander MastrolonardoMichael G. DeGroote School of Medicine, McMaster University, Hamilton, ON, Canada.
Rachel CoubanDept of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, ON, Canada.ORCID https://orcid.org/0000-0001-8672-2845
Paul M O'ByrneDept of Medicine, McMaster University, Hamilton, ON, Canada.ORCID https://orcid.org/0000-0003-0979-281X
Imran SatiaDept of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, ON, Canada satiai@mcmaster.ca.ORCID https://orcid.org/0000-0003-4206-6000

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCough severity represents an important subjective endpoint in assessing the effectiveness of therapies for patients with chronic cough. Although cough-specific quality of life questionnaires exist, a widely available cough severity instrument with established measurement properties remains unavailable.

aimsTo identify and summarise the results of studies reporting on the experience of patients with chronic cough and, in the process, develop a conceptual framework to inform development of a patient-reported outcome measurement (PROM) addressing cough severity.

resultsWe identified 61 eligible studies reporting on patient experience with chronic cough. Studies provided 82 potential items, of which 43 proved unique and relevant to cough severity. The urge-to-cough sensation and the cough symptom itself represented broad domains of cough severity. Two subdomains under urge-to-cough included frequency (1 item) and intensity (1 item). Five subdomains under cough symptoms included control (2 items), frequency (6 items), bout duration (1 item), intensity (8 items), and associated features/sequelae (24 items).

conclusionsOur systematic survey and conceptual framework identified items and domains of cough severity in patients with refractory or unexplained chronic cough. The results support item generation and content validity for a PROM assessing cough severity.

Indexed as

CoughQuality of LifeChronic DiseaseHumansReproducibility of ResultsSurveys and Questionnaires

Identifiers

PMID34261745
PMCPMC9518000

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.