Evidence map›Paper›PMID 34261543›Full record

ReviewAsthma research and practice2021

Asthma and COVID-19: a dangerous liaison?

Carlo Lombardi, Federica Gani, Alvise Berti, Pasquale Comberiati, Diego Peroni, Marcello Cottini

Open access · goldAbstract readReview
In one paragraph

Review in Asthma research and practice, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
2.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 54 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Bronchial Asthma and COVID-19: Etiology, Pathological Triggers, and Therapeutic Considerations.Pathophysiology : the official journal of the International Society for Pathophysiology · 2024
    Review
  6. Article
  7. Prioritizing Asthma Treatment Drugs through Multicriteria Decision Making.International journal of analytical chemistry · 2024
    Article
  8. Review
  9. COVID-19 in Patients with Chronic Lung Disease.Clinics in chest medicine · 2023
    Review
  10. Article
  11. Article
  12. Review
  13. Review
  14. Adult Severe Asthma Registries: A Global and Growing Inventory.Pragmatic and observational research · 2023
    Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Viral Infection and Airway Epithelial Immunity in Asthma.International journal of molecular sciences · 2022
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

Carlo LombardiDepartmental Unit of Allergology, Immunology & Pulmonary Diseases, Fondazione Poliambulanza, Brescia, Italy. carlo.lombardi@poliambulanza.it.
Federica GaniAllergy Outpatients Clinic, Turin, Italy.
Alvise BertiOspedale Santa Chiara and Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Trento, Italy.ORCID http://orcid.org/0000-0002-7831-921X
Pasquale ComberiatiDepartment of Clinical and Experimental Medicine, Section of Pediatrics, University of Pisa, Pisa, Italy.
Diego PeroniThoracic Disease Research Unit, Mayo Clinic, Rochester, MN, USA.
Marcello CottiniAllergy and Pneumology Outpatient Clinic, Bergamo, Italy.
Fondazione Poliambulanza Istituto Ospedaliero · ITMayo Clinic in Florida · USUniversity of Pisa · ITUniversity of Trento · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The coronavirus disease 2019 (COVID-19) pandemic, caused by the new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), provoked the most striking international public health crisis of our time. COVID-19 can cause a range of breathing problems, from mild to critical, with potential evolution to respiratory failure and acute respiratory distress syndrome. Elderly adults and those affected with chronic cardiovascular, metabolic, and respiratory conditions carry a higher risk of severe COVID-19. Given the global burden of asthma, there are well-founded concerns that the relationship between COVID-19 and asthma could represent a "dangerous liaison".Here we aim to review the latest evidence on the links between asthma and COVID-19 and provide reasoned answers to current concerns, such as the risk of developing SARS-CoV-2 infection and/or severe COVID-19 stratified by asthmatic patients, the contribution of type-2 vs. non-type-2 asthma and asthma-COPD overlap to the risk of COVID-19 development. We also address the potential role of both standard anti-inflammatory asthma therapies and new biological agents for severe asthma, such as mepolizumab, reslizumab, and benralizumab, on the susceptibility to SARS-CoV-2 infection and severe COVID-19 outcomes.

Indexed as

AsthmaBiological agentsBiologicsCOVID-19ImmunotherapyPhenotypesSARS-COV-2Therapy

Identifiers

PMID34261543
PMCPMC8279806
OpenAlexW3178148912

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.