ArticleGenome medicine2021
DeepProg: an ensemble of deep-learning and machine-learning models for prognosis prediction using multi-omics data.
Article in Genome medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 150 papers, 3 of them syntheses that pooled it.
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Who cites it
150 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Early risk prediction in endometrial cancer using biomarker and machine learning models: a systematic review and meta-analysis protocol.Systematic reviews · 2026Pooled it
- Survival prediction landscape: an in-depth systematic literature review on activities, methods, tools, diseases, and databases.Frontiers in artificial intelligence · 2024Pooled it
- Application of Deep Learning in Cancer Prognosis Prediction Model.Technology in cancer research & treatmentPooled it
- Single-cell transcriptomics and machine-learning reveal M1 macrophage-driven progression from minimal change disease to focal segmental glomerulosclerosis.Renal failure · 2026Article
- BOMIFA: biologically informed multi-omics integration with graph contrastive learning for cancer prognosis in women.Briefings in bioinformatics · 2026Article
- FastMI-HGNet: A Two-Stream Heterogeneous Graph Neural Network for Multi-Omics Disease Classification.Genes · 2026Article
- The role of artificial intelligence in precision medicine for breast cancer.Discover oncology · 2026Review
- Artificial intelligence-driven multi-omics integration for plant enhancement: advances, challenges, and future perspectives.Functional & integrative genomics · 2026Review
- Cellular immunology data enable clinical severity prediction via supervised machine learning.iScience · 2026Article
- Predicting early-stage breast cancer disease-free survival and adjuvant therapy benefit from multimodal information using deep learning.NPJ breast cancer · 2026Article
- Integrating dietary patterns and metabolomics with machine learning for metabolic syndrome risk assessment in a rural population.NPJ science of food · 2026Article
- Molecular residual disease-based novel modality of postoperative management for non-small-cell lung cancer (REMODEL): Protocol for a prospective multicenter study.Journal of translational internal medicine · 2026Article
- Integrative multi-omics and machine learning reveal glycolysis-related biomarkers driving vascular remodeling in pulmonary arterial hypertension.Molecular and cellular biochemistry · 2026Article
- Progress of metabolomics-centric multi-omics research in medicine.iMetaOmics · 2026Review
- Article
- Toward trustworthy artificial intelligence in multi-omics: a review of reproducibility, stability, and interpretability.Briefings in bioinformatics · 2026Review
- Simultaneous Representation Learning of Multi-Omics and Clinical Outcome Data via a Supervised Knowledge-Guided Bayesian Factor Model.Statistics in medicine · 2026Article
- Prognostic biomarker discovery in pancreatic cancer through hybrid ensemble feature selection and multi-omics data.BioData mining · 2026Article
- Prognostic Factors and Risk Stratification in Malignant Tumor Patients With Sepsis: A Retrospective Cohort Study.Medical science monitor : international medical journal of experimental and clinical research · 2026Article
- Review
90 more citing papers are in PubMed but not listed here.
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Authors and funding
5 authors.
Funding
Abstract
Multi-omics data are good resources for prognosis and survival prediction; however, these are difficult to integrate computationally. We introduce DeepProg, a novel ensemble framework of deep-learning and machine-learning approaches that robustly predicts patient survival subtypes using multi-omics data. It identifies two optimal survival subtypes in most cancers and yields significantly better risk-stratification than other multi-omics integration methods. DeepProg is highly predictive, exemplified by two liver cancer (C-index 0.73-0.80) and five breast cancer datasets (C-index 0.68-0.73). Pan-cancer analysis associates common genomic signatures in poor survival subtypes with extracellular matrix modeling, immune deregulation, and mitosis processes. DeepProg is freely available at https://github.com/lanagarmire/DeepProg.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.