ArticleThe journal of headache and pain2021
Assessment of normalized cerebral blood flow and its connectivity with migraines without aura during interictal periods by arterial spin labeling.
Article in The journal of headache and pain, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Spontaneous brain activity abnormalities in migraine: A meta-analysis of functional neuroimaging.Human brain mapping · 2023Pooled it
- Occipital transcranial direct current stimulation in episodic migraine patients: effect on cerebral perfusion.Scientific reports · 2023Trial
- Effects of Acupuncture on Cerebral Blood Flow in Episodic Migraine Patients Investigated by Arterial Spin Labeling MRI.Neural plasticity · 2026Article
- Abnormal Functional Network Centrality and Causal Connectivity in Migraine Without Aura: A Resting-State fMRI Study.Brain and behavior · 2025Article
- The abnormally increased functional connectivity of the locus coeruleus in migraine without aura patients.BMC research notes · 2024Article
- Perfusion imaging by arterial spin labeling in migraine: A literature review.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2024Review
- Article
- The glymphatic system in migraine and other headaches.The journal of headache and pain · 2024Review
- Increased glymphatic system activity in migraine chronification by diffusion tensor image analysis along the perivascular space.The journal of headache and pain · 2023Article
- Hyperperfusion of bilateral amygdala in patients with chronic migraine: an arterial spin-labeled magnetic resonance imaging study.The journal of headache and pain · 2023Article
- Arterial spin labeling MRI applied to migraine: current insights and future perspectives.The journal of headache and pain · 2023Review
- Altered functional brain network patterns in patients with migraine without aura after transcutaneous auricular vagus nerve stimulation.Scientific reports · 2023Article
- Disrupted resting-state functional connectivity and network topology in mild traumatic brain injury: an arterial spin labelling study.Brain communications · 2023Article
- Exploring the cortical habituation in migraine patients based on contingent negative variation.Frontiers in neurology · 2023Article
- Cerebral perfusion variance in new daily persistent headache and chronic migraine: an arterial spin-labeled MR imaging study.The journal of headache and pain · 2022Article
- Cerebral blood flow alterations in migraine patients with and without aura: An arterial spin labeling study.The journal of headache and pain · 2022Article
- Not Only in Sensorimotor Network: Local and Distant Cerebral Inherent Activity of Chronic Ankle Instability-A Resting-State fMRI Study.Frontiers in neuroscience · 2022Article
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Authors and funding
9 authors.
Funding
Abstract
backgroundMigraine constitutes a global health burden, and its pathophysiology is not well-understood; research evaluating cerebral perfusion and altered blood flow between brain areas using non-invasive imaging techniques, such as arterial spin labeling, have been scarce. This study aimed to assess cerebral blood flow (CBF) and its connectivity of migraine.
methodsThis study enrolled 40 patients with episodic migraine without aura (MwoA), as well as 42 healthy patients as control (HC). Two groups of normalized CBF and CBF connectivity were compared, and the relationship between CBF variation and clinical scale assessment was further evaluated.
resultsIn comparison to HC subjects, MwoA patients exhibited higher CBF in the right middle frontal orbital gyrus (ORBmid.R) and the right middle frontal gyrus, while that in Vermis_6 declined. The increased CBF of ORBmid.R was positively correlated with both the Visual Light Sensitivity Questionnaire-8 (VLSQ-8) and the monthly attack frequency score. In MwoA, significantly decreased CBF connectivity was detected between ORBmid.R and the left superior frontal gyrus, the right putamen, the right caudate, as well as the right angular gyrus. In addition, increased CBF connectivity was observed between the left calcarine cortex and ORBmid.R.
conclusionsOur results indicate that migraine patients exhibit abnormalities in regional CBF and feature CBF connection defects at the resting state. The affected areas involve information perception, information integration, and emotional, pain and visual processing. Our findings might provide important clues for the pathophysiology of migraine.
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