Evidence map›Paper›PMID 34261348›Full record

ArticleJournal of diabetes science and technology2021

Adolescents' Experiences of Using a Smartphone Application Hosting a Closed-loop Algorithm to Manage Type 1 Diabetes in Everyday Life: Qualitative Study.

David Rankin, Barbara Kimbell, Janet M Allen, Rachel E J Besser, Charlotte K Boughton, Fiona Campbell, Daniela Elleri, Julia Fuchs, Atrayee Ghatak, Tabitha Randell and 5 more

Registry-linked trialOpen access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of diabetes science and technology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02871089 (An Open-label, Multicentre, Randomised, Single-period, Parallel Design Study to Assess the Effect of Closed Loop Insulin Delivery From Onset of Type 1 Diabetes in Youth on Residual Beta Cell Function Compared to Standard Insulin Therapy), which is not on this map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02871089 naunknown statusnot on this map

An Open-label, Multicentre, Randomised, Single-period, Parallel Design Study to Assess the Effect of Closed Loop Insulin Delivery From Onset of Type 1 Diabetes in Youth on Residual Beta Cell Function Compared to Standard Insulin Therapy

TypeinterventionalSponsorUniversity of CambridgeRan2017 to 2024Enrolled96ConditionsDiabetes Mellitus, Type 1 DiabetesArmsClosed-loop system (Florence M or CamAPS FX), Multiple Daily Injections
3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 24 citations in OpenAlex.

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  9. "Obviously, Nothing's Gonna Happen in Five Minutes": How Adolescents and Young Adults Infrastructure Resources to Learn Type 1 Diabetes Management.Proceedings of the SIGCHI conference on human factors in computing systems. CHI Conference · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 9 institutions in 1 country.

David RankinUsher Institute, Medical School, University of Edinburgh, UK.ORCID 0000-0002-5835-3402
Barbara KimbellUsher Institute, Medical School, University of Edinburgh, UK.
Janet M AllenWellcome Trust - Medical Research Institute of Metabolic Science, University of Cambridge, UK.
Rachel E J BesserNIHR Oxford Biomedical Research Centre, Oxford University Hospitals NHS Foundation Trust, UK.
Charlotte K BoughtonWellcome Trust - Medical Research Institute of Metabolic Science, University of Cambridge, UK.ORCID 0000-0003-3272-9544
Fiona CampbellSt James's University Hospital, Leeds, UK.
Daniela ElleriRoyal Hospital for Sick Children, Edinburgh, UK.
Julia FuchsWellcome Trust - Medical Research Institute of Metabolic Science, University of Cambridge, UK.ORCID 0000-0002-4497-0979
Atrayee GhatakAlder Hey Children's NHS Foundation Trust, Liverpool, UK.
Tabitha RandellNottingham Children's Hospital, UK.
Ajay ThankamonyAddenbrookes Hospital, Cambridge University Hospitals NHS Foundation Trust, UK.
Nicola TrevelyanSouthampton Children's Hospital, UK.
Malgorzata E WilinskaWellcome Trust - Medical Research Institute of Metabolic Science, University of Cambridge, UK.
Roman HovorkaWellcome Trust - Medical Research Institute of Metabolic Science, University of Cambridge, UK.
Julia LawtonUsher Institute, Medical School, University of Edinburgh, UK.
University of Cambridge · GBUniversity of Edinburgh · GBAlder Hey Children's NHS Foundation Trust · GBCambridge University Hospitals NHS Foundation Trust · GBNottingham City Hospital · GBRoyal Hospital for Children · GBSouthampton Children's Hospital · GBSt James's University Hospital · GBUniversity of Oxford · GB

Funding

Department of Health 14/23/09Wellcome TrustWellcome Trust 100574/Z/12/Z
6 · The paper itself

Abstract

backgroundClosed-loop technology may help address health disparities experienced by adolescents, who are more likely to have suboptimal glycemic control than other age groups and, because of their age, find diabetes self-management particularly challenging. The CamAPS FX closed-loop has sought to address accessibility and usability issues reported by users of previous prototype systems. It comprises small components and a smartphone app used to: announce meal-time boluses, adjust ("boost" or "ease-off") closed-loop insulin delivery, customize alarms, and review/share data. We explored how using the CamAPS FX platform influences adolescents' self-management practices and everyday lives.

methodsEighteen adolescents were interviewed after having ≥6 months experience using the closed-loop platform. Data were analyzed thematically.

resultsParticipants reported feeling less burdened and shackled by diabetes because closed-loop components were easier to carry/wear, finger-pricks were not required, the smartphone app provided a discreet and less stigmatizing way of managing diabetes in public, and they were able to customize alarms. Participants also reported checking and reviewing data more regularly, because they did so when using the smartphone for other reasons. Some reported challenges in school settings where use of personal phones was restricted. Participants highlighted how self-management practices were improved because they could easily review glucose data and adjust closed-loop insulin delivery using the "boost" and "ease-off" functions. Some described how using the system resulted in them forgetting about diabetes and neglecting certain tasks.

conclusionsA closed-loop system with small components and control algorithm on a smartphone app can enhance usability and acceptability for adolescents and may help address the health-related disparities experienced by this age group. However, challenges can arise from using a medical app on a device which doubles as a smartphone.

trial registrationClosed Loop From Onset in Type 1 Diabetes (CLOuD); NCT02871089; https://clinicaltrials.gov/ct2/show/NCT02871089.

Indexed as

Diabetes Mellitus, Type 1AdolescentAlgorithmsBlood GlucoseBlood Glucose Self-MonitoringHumansHypoglycemic AgentsInsulinInsulin Infusion SystemsSmartphoneBlood GlucoseHypoglycemic AgentsInsulinclosed-loopcontinuous glucose monitordisparitiespatient experiencesqualitative methodstype 1 diabetes

Identifiers

PMID34261348
PMCPMC8411472
OpenAlexW3181560487

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.