Evidence map›Paper›PMID 34261344›Full record

ArticleThe journal of histochemistry and cytochemistry : official journal of the Histochemistry Society2021

Expression of Transcription Factor

Heidi Kaprio, Vanina D Heuser, Katri Orte, Mikko Tukiainen, Ilmo Leivo, Maria Gardberg

Open access · hybridAbstract read
In one paragraph

Article in The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 20 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Immunohistochemical evaluation of CREM in CREB-rearranged mesenchymal tumors and their mimics.Virchows Archiv : an international journal of pathology · 2025
    Article
  6. Article
  7. Article
  8. Current drug discovery technologies · 2025
    Article
  9. Article
  10. Article
  11. [High expression of CREM is associated with poor prognosis in gastric cancer patients].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2024
    Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Heidi KaprioDepartment of Pathology, Institute of Biomedicine, Turku University Hospital and University of Turku, Turku, Finland.
Vanina D HeuserDepartment of Pathology, Institute of Biomedicine, Turku University Hospital and University of Turku, Turku, Finland.
Katri OrteDepartment of Pathology, Institute of Biomedicine, Turku University Hospital and University of Turku, Turku, Finland.
Mikko TukiainenAuria Biobank, Turku University Hospital and University of Turku, Turku, Finland.
Ilmo LeivoDepartment of Pathology, Institute of Biomedicine, Turku University Hospital and University of Turku, Turku, Finland.
Maria GardbergDepartment of Pathology, Institute of Biomedicine, Turku University Hospital and University of Turku, Turku, Finland.
Turku University Hospital · FIUniversity of Turku · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cyclic AMP element modulator (CREM) is a transcription factor best known for its intricate involvement in spermatogenesis. The

Indexed as

Adipose TissueAdrenal GlandsCell Line, TumorCerebellumCyclic AMP Response Element ModulatorEndometriumFemaleGene Expression RegulationHEK293 CellsHumansImmunohistochemistryMaleMelanocytesNeoplasmsOncogene Proteins, FusionOrgan SpecificityCREM protein, humanCyclic AMP Response Element ModulatorEWSR1 protein, humanOncogene Proteins, FusionRNA-Binding Protein EWScancerCREBCREMcyclic AMP element modulatorfusion geneICERimmunohistochemistrynormal tissuetranscription factor

Identifiers

PMID34261344
PMCPMC8329441
OpenAlexW3182895972

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.