Evidence map›Paper›PMID 34260723›Full record

ArticleRheumatology (Oxford, England)2022

Evidence and consensus-based recommendations for non-pharmacological treatment of fatigue, hand function loss, Raynaud's phenomenon and digital ulcers in patients with systemic sclerosis.

Juliane K Stöcker, Anne A Schouffoer, Julia Spierings, Marisca R Schriemer, Judith Potjewijd, Lian de Pundert, Frank H J van den Hoogen, Maria W G Nijhuis-van der Sanden, J Bart Staal, Ton Satink and 3 more

Abstract readConsensus Statement
PubMed Full text at PMC Publisher
In one paragraph

Article in Rheumatology (Oxford, England), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Review
  6. Review
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Juliane K StöckerDepartment of Research, Sint Maartenskliniek.ORCID 0000-0002-3852-1157
Anne A SchouffoerDepartment of Rheumatology, Leiden University Medical Center, Leiden.
Julia SpieringsDepartment of Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht, The Netherlands.
Marisca R SchriemerDepartment of Research, Sint Maartenskliniek.
Judith PotjewijdDepartment of Clinical Immunology, Maastricht University Medical Center, Maastricht.
Lian de PundertDepartment of Physical Therapy, Haga Teaching Hospital, The Hague.
Frank H J van den HoogenDepartment of Research, Sint Maartenskliniek.
Maria W G Nijhuis-van der SandenRadboud Institute for Health Sciences, IQ Healthcare, Radboud University Medical Center.
J Bart StaalMusculoskeletal Rehabilitation Research Group, HAN University of Applied Sciences.
Ton SatinkResearch Group Neuro Rehabilitation, HAN University of Applied Sciences, Nijmegen.
Madelon C VonkDepartment of Rheumatic Diseases, Radboud University Medical Center, Nijmegen.
Cornelia H M van den EndeDepartment of Research, Sint Maartenskliniek.ORCID 0000-0002-4352-2824
Arthritis Research and Collaboration Hub study group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveSSc is a complex CTD affecting mental and physical health. Fatigue, hand function loss, and RP are the most prevalent disease-specific symptoms of systemic sclerosis. This study aimed to develop consensus and evidence-based recommendations for non-pharmacological treatment of these symptoms.

methodsA multidisciplinary task force was installed comprising 20 Dutch experts. After agreeing on the method for formulating the recommendations, clinically relevant questions about patient education and treatments were inventoried. During a face-to-face task force meeting, draft recommendations were generated through a systematically structured discussion, following the nominal group technique. To support the recommendations, an extensive literature search was conducted in MEDLINE and six other databases until September 2020, and 20 key systematic reviews, randomized controlled trials, and published recommendations were selected. Moreover, 13 Dutch medical specialists were consulted on non-pharmacological advice regarding RP and digital ulcers. For each recommendation, the level of evidence and the level of agreement was determined.

resultsForty-one evidence and consensus-based recommendations were developed, and 34, concerning treatments and patient education of fatigue, hand function loss, and RP/digital ulcers-related problems, were approved by the task force.

conclusionsThese 34 recommendations provide guidance on non-pharmacological treatment of three of the most frequently described symptoms in patients with systemic sclerosis. The proposed recommendations can guide referrals to health professionals, inform the content of non-pharmacological interventions, and can be used in the development of national and international postgraduate educational offerings.

Indexed as

Raynaud DiseaseScleroderma, SystemicSkin UlcerFatigueHumansUlcerdigital ulcersfatiguehand function lossRPSSc

Identifiers

PMID34260723
PMCPMC8996778

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.