ArticleJournal of the American Medical Informatics Association : JAMIA2021
Integrated digital pathology at scale: A solution for clinical diagnostics and cancer research at a large academic medical center.
Article in Journal of the American Medical Informatics Association : JAMIA, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.
What it found
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The trial behind it
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Who cites it
48 citing papers in PubMed, 77 citations in OpenAlex.
- The Cost of Accessibility: Considerations for Adopting Microscope Camera-Derived Images for Digital and Computational Pathology.Mayo Clinic proceedings. Digital health · 2026Review
- Deployment of AI-driven automated quality control of whole-slide images in a large tertiary cancer center.Journal of pathology informatics · 2026Article
- Lessons learned from three approaches to digital pathology system validation at a large academic medical institution.Journal of pathology informatics · 2026Article
- An automated end-to-end pipeline for the management, de-identification, and distribution of whole-slide images using DICOM: An institutional implementation.Journal of pathology informatics · 2026Article
- Machine Learning Predicts Adequacy of Rapid On-site Evaluation in Fine Needle Aspirations in Lung Cancer Cytology.The American journal of pathology · 2026Article
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- Telepathology and Mobile Health System for Province-Wide Pathology Consultation in Henan, China: Retrospective Evaluation Study.Journal of medical Internet research · 2026Observational
- Assessing the influence of two deep-learning assistance modes on pathologists in cancer identification.Diagnostic pathology · 2026Article
- Establishing dermatopathology encyclopedia DermpathNet with Artificial Intelligence-Based Workflow.Scientific data · 2026Article
- Developing a smart and scalable tool for histopathological education-PATe 2.0.Journal of pathology informatics · 2026Article
- Deep learning-based radiomics and pathomics for decoding tumor microenvironment and predicting immunotherapy outcomes in gastric cancer.Frontiers in immunology · 2026Review
- Applications and challenges of utilizing digital pathology and AI-enabled workflows in clinical trials.Journal of pathology informatics · 2026Review
- Self-supervised stain normalization empowers privacy-preserving and model generalization in digital pathology.NPJ digital medicine · 2025Article
- Nursing Students' Perception of and Readiness for Artificial Intelligence in Saudi Arabia.Nursing open · 2025Article
- Deep Learning-Based Segmentation of Lung Adenocarcinoma Whole-Slide Images for Objective Grading, Tumor Spread Through Air Spaces Identification, and Mutation Prediction.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2025Article
- Implementing digital pathology: qualitative and financial insights from eight leading European laboratories.Virchows Archiv : an international journal of pathology · 2025Article
- An open-source platform for structured annotation and computational workflows in digital pathology research.Scientific reports · 2025Article
- Digital slide scanning at scale: Comparison of whole slide imaging devices in a clinical setting.Journal of pathology informatics · 2025Article
- Automating Colon Polyp Classification in Digital Pathology by Evaluation of a "Machine Learning as a Service" AI Model: Algorithm Development and Validation Study.JMIR formative research · 2025Article
- An equivalency and efficiency study for one year digital pathology for clinical routine diagnostics in an accredited tertiary academic center.Virchows Archiv : an international journal of pathology · 2025Review
Corrections and comments
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Authors and funding
32 authors at 2 institutions in 2 countries.
Funding
Abstract
objectiveBroad adoption of digital pathology (DP) is still lacking, and examples for DP connecting diagnostic, research, and educational use cases are missing. We blueprint a holistic DP solution at a large academic medical center ubiquitously integrated into clinical workflows; researchapplications including molecular, genetic, and tissue databases; and educational processes. MATERIALS AND
methodsWe built a vendor-agnostic, integrated viewer for reviewing, annotating, sharing, and quality assurance of digital slides in a clinical or research context. It is the first homegrown viewer cleared by New York State provisional approval in 2020 for primary diagnosis and remote sign-out during the COVID-19 (coronavirus disease 2019) pandemic. We further introduce an interconnected Honest Broker for BioInformatics Technology (HoBBIT) to systematically compile and share large-scale DP research datasets including anonymized images, redacted pathology reports, and clinical data of patients with consent.
resultsThe solution has been operationally used over 3 years by 926 pathologists and researchers evaluating 288 903 digital slides. A total of 51% of these were reviewed within 1 month after scanning. Seamless integration of the viewer into 4 hospital systems clearly increases the adoption of DP. HoBBIT directly impacts the translation of knowledge in pathology into effective new health measures, including artificial intelligence-driven detection models for prostate cancer, basal cell carcinoma, and breast cancer metastases, developed and validated on thousands of cases.
conclusionsWe highlight major challenges and lessons learned when going digital to provide orientation for other pathologists. Building interconnected solutions will not only increase adoption of DP, but also facilitate next-generation computational pathology at scale for enhanced cancer research.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.