Evidence map›Paper›PMID 34260638›Full record

ArticlePloS one2021

Sero-surveillance for SARS-CoV-2 infection among healthcare providers in four hospitals in Thailand one year after the first community outbreak.

Wanitchaya Kittikraisak, Phunlerd Piyaraj, Apichat Vachiraphan, Thanapat Wongrapee, Somsak Punjasamanvong, Taweewun Hunsawong, Chalinthorn Sinthuwattanawibool, Chaniya Leepiyasakulchai, Pornsak Yoocharoen, Eduardo Azziz-Baumgartner and 2 more

Abstract readMulticenter Study
In one paragraph

Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Wanitchaya KittikraisakInfluenza Program, Thailand Ministry of Public Health - U.S. Centers for Disease Control and Prevention, Nonthaburi, Thailand.ORCID 0000-0002-2295-4388
Phunlerd PiyarajPhramongkutklao College of Medicine, Bangkok, Thailand.ORCID 0000-0003-0166-7336
Apichat VachiraphanBamrasnaradura Infectious Diseases Institute, Nonthaburi, Thailand.
Thanapat WongrapeePhaholpolpayuhasena Hospital, Kanchanaburi, Thailand.
Somsak PunjasamanvongRayong Hospital, Rayong, Thailand.
Taweewun HunsawongVirology Department, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand.
Chalinthorn SinthuwattanawiboolInfluenza Program, Thailand Ministry of Public Health - U.S. Centers for Disease Control and Prevention, Nonthaburi, Thailand.
Chaniya LeepiyasakulchaiFaculty of Medical Technology, Mahidol University, Nakhon Pathom, Thailand.
Pornsak YoocharoenDepartment of Disease Control, Ministry of Public Health, Nonthaburi, Thailand.
Eduardo Azziz-BaumgartnerInfluenza Division, U.S. Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America.
Joshua A MottInfluenza Program, Thailand Ministry of Public Health - U.S. Centers for Disease Control and Prevention, Nonthaburi, Thailand.
Suthat ChottanapundDepartment of Disease Control, Ministry of Public Health, Nonthaburi, Thailand.

Funding

CGH CDC HHS U01 GH002084NIH HHS 1U01 GH002084
6 · The paper itself

Abstract

backgroundThailand was the first country outside China to report SARS-CoV-2 infected cases. Since the detection of the first imported case on January 12th, 2020 to the time this report was written, Thailand experienced two waves of community outbreaks (March-April 2020 and December 2020-March 2021). We examined prevalence of SARS-CoV-2 seropositivity among healthcare providers (HCPs) in four hospitals approximately one year after SARS-CoV-2 first detected in Thailand. By March 2021, these hospitals have treated a total of 709 coronavirus disease 2019 (COVID-19) patients.

methodsBlood specimens, collected from COVID-19 unvaccinated HCPs during January-March 2021, were tested for the presence of SARS-CoV-2 immunoglobulin G (IgG) antibodies to nucleocapsid (IgG-nucleocapsid) and spike (IgG-spike) proteins using Euroimmune® enzyme-linked immunosorbent assays.

resultsOf 600 HCPs enrolled, 1 (0.2%) tested positive for the SARS-CoV-2 IgG-spike antibodies, but not the IgG-nucleocapsid.

conclusionThe presence of SARS-CoV-2 IgG antibodies was rare in this sample of HCPs, suggesting that this population remains susceptible to SARS-CoV-2 infection.

Indexed as

Health PersonnelAdultAntibodies, ViralCoronavirus Nucleocapsid ProteinsCOVID-19FemaleHumansMaleMiddle AgedPopulation SurveillanceProspective StudiesSARS-CoV-2Seroepidemiologic StudiesSpike Glycoprotein, CoronavirusThailandAntibodies, ViralCoronavirus Nucleocapsid ProteinsSpike Glycoprotein, Coronavirusspike glycoprotein, SARS-CoV

Identifiers

PMID34260638
PMCPMC8279322

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.