Evidence map›Paper›PMID 34260376›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2021

A platform utilizing

Kewa Jiang, Jiyang Zhang, Yuping Huang, Yingzheng Wang, Shuo Xiao, M Kyle Hadden, Teresa K Woodruff, Jianjun Sun

Open access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 16 citations in OpenAlex.

  1. TransgenicPharmaceuticals (Basel, Switzerland) · 2024
    Article
  2. Finishing the egg.Genetics · 2024
    Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Kewa JiangDepartment of Physiology and Neurobiology, University of Connecticut, Storrs, CT 06269.ORCID 0000-0002-6896-1671
Jiyang ZhangDepartment of Obstetrics and Gynecology, Northwestern University, Chicago, IL 60611.
Yuping HuangDepartment of Physiology and Neurobiology, University of Connecticut, Storrs, CT 06269.ORCID 0000-0001-7942-9704
Yingzheng WangDepartment of Pharmacology and Toxicology, Ernest Mario School of Pharmacy, Environmental and Occupational Health Sciences Institute, Rutgers University, Piscataway, NJ 08854.ORCID 0000-0001-8232-4524
Shuo XiaoDepartment of Pharmacology and Toxicology, Ernest Mario School of Pharmacy, Environmental and Occupational Health Sciences Institute, Rutgers University, Piscataway, NJ 08854.
M Kyle HaddenDepartment of Pharmaceutical Sciences, School of Pharmacy, University of Connecticut, Storrs, CT 06269.ORCID 0000-0001-9482-1712
Teresa K WoodruffDepartment of Obstetrics and Gynecology, Northwestern University, Chicago, IL 60611.ORCID 0000-0002-1197-3399
Jianjun SunDepartment of Physiology and Neurobiology, University of Connecticut, Storrs, CT 06269; jianjun.sun@uconn.edu.ORCID 0000-0002-6015-738X
University of Connecticut · USNorthwestern University · USRutgers, The State University of New Jersey · US

Funding

Translational Research Support CoreP30ES005022 · NIEHS · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI PANOS G. GEORGOPOULOS · 1988 to 2026
$47.4M
Genetic interrogation of conserved follicular factors for matrix metalloproteinase regulation and ovulationR01HD086175 · NICHD · UNIVERSITY OF CONNECTICUT STORRS · PI SUN, JIANJUN · 2016 to 2020
$1.7M
Physiological Functions of Female Reproductive Tract SecretionsR01HD097206 · NICHD · UNIVERSITY OF CONNECTICUT STORRS · PI SUN, JIANJUN · 2020 to 2025
$1.6M
NICHD NIH HHS R01 HD086175NICHD NIH HHS R01 HD097206NIEHS NIH HHS P30 ES005022
6 · The paper itself

Abstract

A significant unmet need for new contraceptive options for both women and men remains due to side-effect profiles, medical concerns, and the inconvenience of many currently available contraceptive products. Unfortunately, the development of novel nonsteroidal female contraceptive medicine has been stalled in the last couple of decades due to the lack of effective screening platforms.

Indexed as

Contraceptive AgentsAnimalsBiological AssayChlorpromazineDexmedetomidineDrosophila melanogasterDrug ApprovalFemaleHormonesMiceOctopamineOvarian FollicleOvulationUnited StatesUnited States Food and Drug AdministrationChlorpromazineContraceptive AgentsDexmedetomidineHormonesOctopaminechlorpromazinecontraceptive screeningfollicle rupturenonsteroidal contraceptives

Identifiers

PMID34260376
PMCPMC8285897
OpenAlexW3178803393

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.