Evidence map›Paper›PMID 34259960›Full record

ArticleInternational ophthalmology2021

Systemic oxidative stress biomarkers in patients with vitreomacular traction syndrome.

Deniz Kilic, Derya Kocer, Ender Sırakaya, Bekir Küçük, Esra Vural, Soner Guven, Necati Duru

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In one paragraph

Article in International ophthalmology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 88% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Deniz KilicDepartment of Ophthalmology, Kayseri City Training and Research Hospital, Health Science University, Yakut Region, 3844 Street, House Number: 20/16, 38001, Kayseri, Turkey. dnz_kilic@hotmail.com.ORCID http://orcid.org/0000-0003-4153-5127
Derya KocerDepartment of Biochemistry, Kayseri City Training and Research Hospital, Health Science University, Kayseri, Turkey.
Ender SırakayaDepartment of Ophthalmology, Kayseri City Training and Research Hospital, Health Science University, Yakut Region, 3844 Street, House Number: 20/16, 38001, Kayseri, Turkey.
Bekir KüçükDepartment of Ophthalmology, Kayseri City Training and Research Hospital, Health Science University, Yakut Region, 3844 Street, House Number: 20/16, 38001, Kayseri, Turkey.
Esra VuralDepartment of Ophthalmology, Kayseri City Training and Research Hospital, Health Science University, Yakut Region, 3844 Street, House Number: 20/16, 38001, Kayseri, Turkey.
Soner GuvenDepartment of Ophthalmology, Kayseri City Training and Research Hospital, Health Science University, Yakut Region, 3844 Street, House Number: 20/16, 38001, Kayseri, Turkey.
Necati DuruDepartment of Ophthalmology, Kayseri City Training and Research Hospital, Health Science University, Yakut Region, 3844 Street, House Number: 20/16, 38001, Kayseri, Turkey.
Kayseri Eğitim ve Araştırma Hastanesi · TR

Funding

Health Science University, Kayseri City Training and Research Hospital, Foundation of Scientific Research Support funded this study 2019-22
6 · The paper itself

Abstract

purposeTo evaluate whether the systemic oxidative stress biomarkers increased in patients with vitreomacular traction syndrome (VMT).

methodsThis study compared 25 patients diagnosed with VMT with 20 healthy controls. As a biomarker of systemic oxidative stress, malondialdehyde (MDA) was measured. Total oxidant status (TOS) and total antioxidant status (TAS) were measured to evaluate the systemic oxidant status.

resultsSerum MDA values were significantly higher among the patients (p < 0.001). The ideal cut-off value for MDA was determined to be 22.1 µmol/L, with 80% sensitivity and 75% specificity. The between-group differences were not statistically significant for TOS or TAS (p = 0.326 and p = 0.698, respectively).

conclusionIncreased MDA levels suggest that systemic oxidative stress may play a role in VMT.

Indexed as

Oxidative StressTractionAntioxidantsBiomarkersHumansOxidantsAntioxidantsBiomarkersOxidantsMalondialdehydeOxidative stressTotal antioxidant statusTotal oxidant statusVitreomacular traction syndrome

Identifiers

PMID34259960
OpenAlexW3180772908

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.