ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2021
Iatrogenic muscle damage in transforaminal lumbar interbody fusion and adjacent segment degeneration: a comparative finite element analysis of open and minimally invasive surgeries.
Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Advances in Musculoskeletal Modeling of the Thoraco-Lumbar Spine: A Comprehensive Systematic Review.Annals of biomedical engineering · 2025Pooled it
- Is unilateral pedicle screw fixation as effective as bilateral pedicle screw fixation in transforaminal lumbar interbody fusion: a meta-analysis of randomized controlled trials.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2023Pooled it
- Paraspinal muscular fat infiltration was associated with the development of adjacent segmental disease after microsurgical decompression without fusion for single-level lumbar spinal stenosis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Effects of thoracolumbar fracture combined with muscle injury on long-term outcome and prognosis: a retrospective study.BMC surgery · 2026Article
- Biomechanical effects of different bone conditions on oblique lumbar interbody fusion augmented with various fixation options: a finite element analysis.Frontiers in bioengineering and biotechnology · 2026Article
- A finite element-based comparative dynamic biomechanical study of a novel oblique lateral locking plate system (OLLPS) versus traditional internal fixations for oblique lumbar interbody fusion (OLIF) under whole-body vibration.Frontiers in bioengineering and biotechnology · 2026Article
- Biomechanical evaluation of a novel L-shaped side-locking plate combined with OLIF: a finite element analysis considering 3 different bone densities.Frontiers in surgery · 2026Article
- A Muscle-Driven Spine Model for Predictive Simulations in the Design of Spinal Implants and Lumbar Orthoses.Bioengineering (Basel, Switzerland) · 2025Article
- Biomechanical Evaluation of the Effect of MIS and COS Surgical Techniques on Patients with Spondylolisthesis using a Musculoskeletal Model.Journal of biomedical physics & engineering · 2025Article
- Biomechanical evaluation of oblique lateral interbody fusion with various fixation methods for degenerative lumbar scoliosis: a finite element analysis considering different bone densities.Frontiers in bioengineering and biotechnology · 2025Article
- For severe and rigid adult idiopathic scoliosis, does an optimal extent of posterior intervertebral release exist? A finite element analysis.Frontiers in bioengineering and biotechnology · 2025Article
- Biomechanical analysis of adjacent segments after correction surgery for adult idiopathic scoliosis: a finite element analysis.Scientific reports · 2024Article
- Pelvic Ring Fractures: A Biomechanical Comparison of Sacral and Lumbopelvic Fixation Techniques.Bioengineering (Basel, Switzerland) · 2024Article
- Comparison between minimally invasive and open transforaminal lumbar interbody fusion for the treatment of multi‑segmental lumbar degenerative disease: A systematic evaluation and meta‑analysis.Experimental and therapeutic medicine · 2024Article
- Changes in psoas and posterior paraspinal muscle morphology after standalone lateral lumbar interbody fusion: a quantitative MRI-based analysis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2023Article
- Recent Advances in Coupled MBS and FEM Models of the Spine-A Review.Bioengineering (Basel, Switzerland) · 2023Review
- Muscle-driven forward dynamic active hybrid model of the lumbosacral spine: combined FEM and multibody simulation.Frontiers in bioengineering and biotechnology · 2023Article
- The association between morphological characteristics of paraspinal muscle and spinal disorders.Annals of medicine · 2023Review
- Adjacent segments biomechanics following lumbar fusion surgery: a musculoskeletal finite element model study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2022Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeLumbar procedures for Transforaminal Lumbar Interbody Fusion (TLIF) range from open (OS) to minimally invasive surgeries (MIS) to preserve paraspinal musculature. We quantify the biomechanics of cross-sectional area (CSA) reduction of paraspinal muscles following TLIF on the adjacent segments.
methodsROM was acquired from a thoracolumbar ribcage finite element (FE) model across each FSU for flexion-extension. A L4-L5 TLIF model was created. The ROM in the TLIF model was used to predict muscle forces via OpenSim. Muscle fiber CSA at L4 and L5 were reduced from 4.8%, 20.7%, and 90% to simulate muscle damage. The predicted muscle forces and ROM were applied to the TLIF model for flexion-extension. Stresses were recorded for each model.
resultsIncreased ROM was present at the cephalad (L3-L4) and L2-L3 level in the TLIF model compared to the intact model. Graded changes in paraspinal muscles were seen, the largest being in the quadratus lumborum and multifidus. Likewise, intradiscal pressures and annulus stresses at the cephalad level increased with increasing CSA reduction.
conclusionsCSA reduction during the TLIF procedure can lead to adjacent segment alterations in the spinal element stresses and potential for continued back pain, postoperatively. Therefore, minimally invasive techniques may benefit the patient.
Indexed as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.