ArticleAnalytical and bioanalytical chemistry2021
Multiplexing neurochemical detection with carbon fiber multielectrode arrays using fast-scan cyclic voltammetry.
Article in Analytical and bioanalytical chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Parylenes in bioanalytical and cell culture applications.Analytical and bioanalytical chemistry · 2026Review
- Multiplexer-based system development for multichannel neurochemical sensing.Biomedical engineering letters · 2026Article
- Pyrolyzed Parylene Electrodes for Detection of Tryptophan, Tyrosine, and Gonadotropin-Releasing Hormone.ACS measurement science au · 2026Article
- Machine Learning for Neurotransmitter Monitoring by Fast Voltammetry: Current and Future Prospects.ACS chemical neuroscience · 2026Review
- Recent applications of parylene and pyrolyzed parylene in sensors and devices: a review.Analytical and bioanalytical chemistry · 2026Review
- Progress toward Multianalyte Neurochemical Detection: Techniques and Applications.ACS chemical neuroscience · 2025Review
- SeroWare: An Open-Source Software Suite for Voltammetry Data Acquisition and Analysis.ACS chemical neuroscience · 2025Article
- Carbon Electrode Sensor for the Measurement of Cortisol with Fast-Scan Cyclic Voltammetry.Biosensors · 2023Article
- Letting the little light of mind shine: Advances and future directions in neurochemical detection.Neuroscience research · 2022Review
- High resolution voltammetric and field-effect transistor readout of carbon fiber microelectrode biosensors.Sensors & diagnostics · 2022Article
- Bi-ECDAQ: An electrochemical dual-immuno-biosensor accompanied by a customized bi-potentiostat for clinical detection of SARS-CoV-2 Nucleocapsid proteins.Biosensors & bioelectronics · 2022Article
- Modified Sawhorse Waveform for the Voltammetric Detection of Oxytocin.Journal of the Electrochemical Society · 2022Article
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2 authors.
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Abstract
Carbon fiber microelectrodes (CFMEs) have been extensively used to measure neurotransmitters with fast-scan cyclic voltammetry (FSCV) due to their ability to adsorb cationic monoamine neurotransmitters. Although FSCV, in tandem with CFMEs, provides high temporal and spatial resolution, only single-channel potentiostats and electrodes have been primarily utilized. More recently, the need and use of carbon fiber multielectrode arrays has risen to target multiple brain regions. Previous studies have shown the ability to detect dopamine using multielectrode arrays; however, they are not readily available to the scientific community. In this work, we interfaced a carbon fiber multielectrode array (MEA or multielectrode array), to a commercially available four-channel potentiostat for multiplexing neurochemical measurements. The MEA's relative performance was compared to single CFMEs where dopamine detection was found to be adsorption controlled to the electrode's surface. Multiple waveforms were applied to each fiber of the multielectrode array simultaneously to detect different analytes on each electrode of the array. A proof of concept ex vivo experiment showed that the multielectrode array could record redox activity in different areas within the mouse caudate putamen and detect dopamine in a 3-mm
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