Evidence map›Paper›PMID 34259637›Full record

ArticleJournal of medical Internet research2021

Behavioral Activation and Depression Symptomatology: Longitudinal Assessment of Linguistic Indicators in Text-Based Therapy Sessions.

Hannah A Burkhardt, George S Alexopoulos, Michael D Pullmann, Thomas D Hull, Patricia A Areán, Trevor Cohen

Registry-linked trialAbstract read
In one paragraph

Article in Journal of medical Internet research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05194722 (Optimizing Implementation of Mental Health Intervention Within Orthopedic Care), which is not on this map. Cited by 22 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05194722 nacompletednot on this mapstarted 2022, after this paper: background citation

Optimizing Implementation of Mental Health Intervention Within Orthopedic Care

TypeinterventionalSponsorWashington University School of MedicineRan2022 to 2022Enrolled30ConditionsAnxiety, Depression, Back Pain, Neck PainArmsWysa mobile app
3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Scoping review on natural language processing applications in counselling and psychotherapy.British journal of psychology (London, England : 1953) · 2026
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  14. Deep Learning and Geriatric Mental Health.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hannah A BurkhardtDepartment of Biomedical Informatics and Medical Education, University of Washington, Seattle, WA, United States.ORCID 0000-0002-9386-5569
George S AlexopoulosWeill Cornell Institute of Geriatric Psychiatry, Weill Cornell Medicine, White Plains, NY, United States.ORCID 0000-0001-5677-7001
Michael D PullmannALACRITY Center, Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA, United States.ORCID 0000-0001-8404-864X
Thomas D HullTalkspace, New York, NY, United States.ORCID 0000-0001-8275-6765
Patricia A AreánALACRITY Center, Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA, United States.ORCID 0000-0001-5971-6319
Trevor CohenDepartment of Biomedical Informatics and Medical Education, University of Washington, Seattle, WA, United States.ORCID 0000-0003-0159-6697

Funding

University of Washington Biomedical Informatics and Data Science Research Training ProgramT15LM007442 · NLM · UNIVERSITY OF WASHINGTON · PI JOHN H. GENNARI, Andrea L. Hartzler · 2002 to 2026
$19.6M
UW ALACRITY Center for Psychosocial Interventions ResearchP50MH115837 · NIMH · UNIVERSITY OF WASHINGTON · PI IAN Moore BENNETT · 2018 to 2026
$18.2M
Relief: A Behavioral Intervention for Depression and Chronic Pain for Primary Care PracticesP50MH113838 · NIMH · WEILL MEDICAL COLL OF CORNELL UNIV · PI ALEXOPOULOS, GEORGE S · 2017 to 2020
$5.7M
Target engagement of a reward exposure therapy (Engage) for late life depressionR01MH102252 · NIMH · WEILL MEDICAL COLL OF CORNELL UNIV · PI ALEXOPOULOS, GEORGE S · 2014 to 2018
$2.0M
NIMH NIH HHS P50 MH113838NIMH NIH HHS P50 MH115837NIMH NIH HHS R01 MH102252NLM NIH HHS T15 LM007442
6 · The paper itself

Abstract

backgroundBehavioral activation (BA) is rooted in the behavioral theory of depression, which states that increased exposure to meaningful, rewarding activities is a critical factor in the treatment of depression. Assessing constructs relevant to BA currently requires the administration of standardized instruments, such as the Behavioral Activation for Depression Scale (BADS), which places a burden on patients and providers, among other potential limitations. Previous work has shown that depressed and nondepressed individuals may use language differently and that automated tools can detect these differences. The increasing use of online, chat-based mental health counseling presents an unparalleled resource for automated longitudinal linguistic analysis of patients with depression, with the potential to illuminate the role of reward exposure in recovery.

objectiveThis work investigated how linguistic indicators of planning and participation in enjoyable activities identified in online, text-based counseling sessions relate to depression symptomatology over time.

methodsUsing distributional semantics methods applied to a large corpus of text-based online therapy sessions, we devised a set of novel BA-related categories for the Linguistic Inquiry and Word Count (LIWC) software package. We then analyzed the language used by 10,000 patients in online therapy chat logs for indicators of activation and other depression-related markers using LIWC.

resultsDespite their conceptual and operational differences, both previously established LIWC markers of depression and our novel linguistic indicators of activation were strongly associated with depression scores (Patient Health Questionnaire [PHQ]-9) and longitudinal patient trajectories. Emotional tone; pronoun rates; words related to sadness, health, and biology; and BA-related LIWC categories appear to be complementary, explaining more of the variance in the PHQ score together than they do independently.

conclusionsThis study enables further work in automated diagnosis and assessment of depression, the refinement of BA psychotherapeutic strategies, and the development of predictive models for decision support.

Indexed as

DepressionLinguisticsEmotionsHumansLanguageSemanticsbehavioral activationdepressiondigital interventionsmental healthnatural language processingtext analysis

Identifiers

PMID34259637
PMCPMC8319778

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.