Evidence map›Paper›PMID 34259627›Full record

ArticleeLife2021

CEP78 functions downstream of CEP350 to control biogenesis of primary cilia by negatively regulating CP110 levels.

André Brás Gonçalves, Sarah Kirstine Hasselbalch, Beinta Biskopstø Joensen, Sebastian Patzke, Pernille Martens, Signe Krogh Ohlsen, Mathieu Quinodoz, Konstantinos Nikopoulos, Reem Suleiman, Magnus Per Damsø Jeppesen and 6 more

Open access · goldAbstract read
In one paragraph

Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
5.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 43 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 4 countries.

André Brás GonçalvesDepartment of Biology, Section for Cell Biology and Physiology, University of Copenhagen, Copenhagen, Denmark.
Sarah Kirstine Hasselbalch *Department of Biology, Section for Cell Biology and Physiology, University of Copenhagen, Copenhagen, Denmark.
Beinta Biskopstø Joensen *Department of Biology, Section for Cell Biology and Physiology, University of Copenhagen, Copenhagen, Denmark.
Sebastian PatzkeDepartment of Radiation Biology, Institute for Cancer Research, Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway.
Pernille MartensDepartment of Biology, Section for Cell Biology and Physiology, University of Copenhagen, Copenhagen, Denmark.
Signe Krogh OhlsenDepartment of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark.
Mathieu QuinodozInstitute of Molecular and Clinical Ophthalmology Basel (IOB), Basel, Switzerland.
Konstantinos NikopoulosDepartment of Computational Biology, University of Lausanne, Lausanne, Switzerland.
Reem SuleimanDepartment of Biology, Section for Cell Biology and Physiology, University of Copenhagen, Copenhagen, Denmark.
Magnus Per Damsø JeppesenDepartment of Biology, Section for Cell Biology and Physiology, University of Copenhagen, Copenhagen, Denmark.
Catja WeissDepartment of Biology, Section for Cell Biology and Physiology, University of Copenhagen, Copenhagen, Denmark.
Søren Tvorup ChristensenDepartment of Biology, Section for Cell Biology and Physiology, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0001-5004-304X
Carlo RivoltaInstitute of Molecular and Clinical Ophthalmology Basel (IOB), Basel, Switzerland.
Jens S AndersenDepartment of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark.
Pietro FarinelliDepartment of Biology, Section for Cell Biology and Physiology, University of Copenhagen, Copenhagen, Denmark.
Lotte Bang PedersenDepartment of Biology, Section for Cell Biology and Physiology, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0002-9749-3758
University of Copenhagen · DKUniversity of Leicester · GBUniversity of Southern Denmark · DKOslo University Hospital · NOUniversity of Lausanne · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

CEP78 is a centrosomal protein implicated in ciliogenesis and ciliary length control, and mutations in the

Indexed as

Cell Cycle ProteinsCiliaGene Knockout TechniquesHumansMicrotubule-Associated ProteinsMicrotubule ProteinsNuclear ProteinsPhosphoproteinsUbiquitinationCCP110 protein, humanCell Cycle ProteinsCEP350 protein, humanCEP78 protein, humanMicrotubule-Associated ProteinsMicrotubule ProteinsNuclear ProteinsPhosphoproteinscell biologycentrosomeCEP350CEP78ciliaCP110humanubiquitin

Identifiers

PMID34259627
PMCPMC8354638
OpenAlexW3178751415

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.